DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk22 and ppk16

DIOPT Version :9

Sequence 1:	NP_733051.2	Gene:	ppk22 / 318593	FlyBaseID:	FBgn0051105	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	568	Identity:	138/568 - (24%)
Similarity:	236/568 - (41%)	Gaps:	87/568 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KLASTSNAIWWIKNPKAAGEHN--SKGKRKESLGSAFCLDMADLVRNISLQGYNKLLSPDLTLGQ 65
            ::|:|  ||....:|.....||  ....|...:|..|..:|.:..:..||.|::.:...|::..:
  Fly    18 QMATT--AIHRRSHPMHNHSHNPIQPQHRFRQIGEWFTENMRNYCQTTSLHGFSYITRQDISRHE 80

  Fly    66 RLIWLLVHMATTVSLIVVLSLTWEQFVAQSFVTNLKDPLFPVENVPFPAVSICPNNRISRQAVIQ 130
            |..||:|.:...::.||::.::|........||.::...||..|:|||||:||..|:||:...:.
  Fly    81 RWFWLVVVILAIITSIVLVVVSWYWSQETPTVTVIESSHFPTWNIPFPAVTICNFNKISKSKALS 145

  Fly   131 YAEELRLNSPVIRPVEYFLERLRFFREFYTHVGVVVDTDDFITFQTFLDVFGTWNNETFFDTRRI 195
            ..:::::...:.|.     |....|......|..::..|....:...|.:    ||.|.   .|:
  Fly   146 LLDQMQVPVGINRS-----ELHNLFNLTLLPVDTMISNDSLQKYDRILSL----NNLTL---NRL 198

  Fly   196 MKMLTPRCQGFVLKCTVANVEVPCFSKDAFQDSLTMYGPCCTFN------------MENKLKKRH 248
            .:.|:|.|...:..|....:...|  :..||...||.|.|||||            :..::.||.
  Fly   199 TQQLSPDCIEMISSCIWKGINTRC--ESLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRP 261

  Fly   249 FKNRLASSELGLKVVLNDSHVDYFAPILNTNGYIVMIHNAENYASVYSSNVLEMFPGQGEDSYIA 313
            ::........||.|:||....||:....:..|:.:::|:|.|            ||.:..::.:
  Fly   262 YRVTGCGYPTGLSVLLNPMISDYYGTFFSGFGFRLLLHDAYN------------FPDENSETKV- 313

  Fly   314 VCARVVDTDDSLKSFSPFS--------------RRCYFEYEAQNPIHEQLMNTYSL-SYTFPNCI 363
                |..|.:|....:|.|              |.|.|..|         |..:.| .|:|.||:
  Fly   314 ----VTTTRESFVRINPESTYATNDIRRMDLSLRNCLFGSE---------MTMHGLRRYSFINCM 365

  Fly   364 TRCRIRSIIALCRCLPFQMPLQLVENLDGVVYCTLGHVSCLNQYIFKWRNILTERHIVNGLEREI 428
            ..||:|..:.||.|||     ..|.|......|.:...:|:......:.:.|...:....:.||
  Fly   366 FECRVRMTVDLCGCLP-----PYVYNNGSYKVCGVLQTNCIIHSKRLFSHALANLNFSLSIVRE- 424

  Fly   429 EEALYCPQCLPSCRDVQY--EVSMSALPIDNYLATLKLDENNETEFGTDISVLRVYFGDPHAQYY 491
            .::..| .|||.|:...|  |.:...|.| :|.|......|     .||..:|.|:|.|..:..|
  Fly   425 TDSFPC-GCLPDCQSNHYVSESTTGRLDI-SYFANRPTFNN-----ATDRILLHVFFSDLMSTRY 482

  Fly   492 IRLLNNTWFEVFSTIGNIMSIFVGFSMVAIFEILFFVT-KYIYKGCNR 538
            ...:...|....::.|.::.:.:|||:|..||.::|:| :.::...||
  Fly   483 RTDIFQNWLSALASFGGLLGLIMGFSIVTAFEFIYFLTFRPVFNYINR 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:279230	123/509 (24%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456686
Domainoid	1	1.000	94	1.000	Domainoid score	I4697
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I3586
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	7	6.890