DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk22 and ppk11

DIOPT Version :9

Sequence 1:	NP_733051.2	Gene:	ppk22 / 318593	FlyBaseID:	FBgn0051105	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001334672.1	Gene:	ppk11 / 34299	FlyBaseID:	FBgn0065109	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	123/549 - (22%)
Similarity:	211/549 - (38%)	Gaps:	135/549 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PKAAG---EHNSKGKRKESLGSAFCLDMADLVRNISLQGYNKLLSPDLTLG----QRLI-WLLVH 73
            ||..|   ..|..|..|...|.....:||      |:.|::      :.:|    ||:: |||:.
  Fly    72 PKFLGFLQARNDDGLCKRKTGFEIYCEMA------SIHGFH------IFVGAKTWQRILWWLLIC 124

  Fly    74 MATTVS---LIVVLSLTWEQFVAQSFVTNLKDPLFPVENVPFPAVSICPNNRISRQAVIQYAEEL 135
            .|..:|   :|:.||::.|....:...|.:|    |...||||||:||..|          .:|.
  Fly   125 NAVLLSFTLVIMSLSMSKETPTIRFIDTMMK----PTAEVPFPAVTICGFN----------TKEW 175

  Fly   136 RLNSPVIRPVEYFLERLRFFREFYTHVGVVVDTDDFITFQTFLDVFGTWNNETFFDTRRIMKMLT 200
            ..:|.::..                                        .|.::.:.  :..:..
  Fly   176 MNSSQIVNQ----------------------------------------RNASWLEL--LEDLAL 198

  Fly   201 PRCQGFVLKCTVANVEVPCFSKDAFQDSLTM-YGPCCTFNMENKLKKRHFKNRLASSELGLKVVL 264
            |.|....: |...|..|.|.  |..|...|: ...||:||         :..:|.||.||:..||
  Fly   199 PICPQIKI-CQWDNRMVNCL--DQLQPIWTLDQRLCCSFN---------YNKQLFSSYLGVSFVL 251

  Fly   265 NDSHVDYFAPILNTNGYIVMIHNAENYASVYSSNVLEMFPGQGEDSYIAVCARVVDTDDSLKSFS 329
            ..:  |.......:.|:.|:||.:....:..:..|  ..||: .|::|.:...:.....:||..|
  Fly   252 RSN--DEILQSSKSAGFEVLIHESHEIPNGATPRV--FVPGE-SDAHIMLRPYINRFTKNLKGLS 311

  Fly   330 PFSRRCYFEYEAQ---NPIHEQLMNTYSLSYTFPNCITRCRIRSIIALCRCLPFQMPLQLVENLD 391
            ...|.|||..|.:   :.::.|:           ||:..||..||:..|.|:|.:.|::     .
  Fly   312 LQKRGCYFSTERRLILSDVYNQI-----------NCLAECRTESILKSCGCIPPKSPIE-----K 360

  Fly   392 GVVYCTLGHVSCLNQYIFKWRNILTERHIVNGLEREIEEALYCPQCLPSCRDVQYEVSMSALPID 456
            ..:.|.|..:.|:..:        ....|::|.::..:       |||.|...:||.......|.
  Fly   361 SWLICDLKQMQCVIDF--------DHDEIISGEQKNCD-------CLPPCEFNRYEFQSDIRFIK 410

  Fly   457 NYLATLKLDENNETEFGTDISVLRVYFGDPHAQYYIRLLNNTWFEVFSTIGNIMSIFVGFSMVAI 521
            ..:....::.:|: |...::.| |||:....|:..:..:...|.....|.|.|..:|:|.|.|::
  Fly   411 GMINNSIVNTSNQ-ETTNEVRV-RVYYDSAIAEELLLDVYENWLTFIGTFGGITGLFMGCSFVSV 473

  Fly   522 FEILFFVTKYIYKGCNRMVEQNIMDRKAK 550
            ||::||  ..:...||.:..|.|:.|:.:
  Fly   474 FELIFF--SCVRPTCNWLTRQQILWRRRR 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:279230	107/492 (22%)
ppk11	NP_001334672.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456684
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5132
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.890