DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk22 and ppk13

DIOPT Version :9

Sequence 1:	NP_733051.2	Gene:	ppk22 / 318593	FlyBaseID:	FBgn0051105	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	108/504 - (21%)
Similarity:	195/504 - (38%)	Gaps:	93/504 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DLVRNISLQGYNKLLSPDLTLGQRLIWLLVHMATTVS--LIVVLSLTWEQFVAQSFVTNLKDPLF 105
            :.::|.:|.|...::..|.:..:|:.|::..:|:..:  |::..||:..:..|.|||.   :..|
  Fly     9 EYLKNSTLHGARFIVDKDASWIERIFWVICLVASWYASWLLIKASLSAFENNAISFVV---ESSF 70

  Fly   106 PVENVPFPAVSICPNNRISRQAVIQYAEELRLNSPVIRPVEYFLERLRFFREFYTHVGVVVDTDD 170
            ...|..|||:.:|.:..:.|   ||...|....:.....:|..|..:.|||....|. |...:.:
  Fly    71 RDWNTNFPAIIVCESKNMDR---IQEVAEQLWGADHDFTLEEVLSEIAFFRGESYHT-VHECSGE 131

  Fly   171 FITFQTFLDVFGTWNNETFFDTRRIMKMLTPRCQGFVLKCTVANVEVPCFSKDAFQDSLTMYGPC 235
            .:|...|      ::|.:::     .:::...|...:..|...|....|..  .|....|..|.|
  Fly   132 EVTASCF------YSNFSYY-----AELVRSSCVDSISNCEWNNKPFECCK--YFHRMETELGIC 183

  Fly   236 CTFNM----ENKLKKRHFKNRLASSELGLKVVLNDSHVDYFAPILNTNGYIVMIHNAENYASV-- 294
            ...|.    :.|:.|.:..:...|....||:.|   |.:....||.|.....::....::..|
  Fly   184 YAINSMQAGKPKMPKLNMYSNRGSGPGALKMEL---HTEATVFILGTEEVPTLVTPKTDFLVVGP 245

  Fly   295 YSSNVLEMFPGQGEDSYIAVCARVVDTDDSLKSFSPFSRRCYFEYEAQNPIHEQLMNTYSLSYTF 359
            |.|.|          .||:  .|.::.|:.::..|...|.|.|..|....:|:        .|::
  Fly   246 YISFV----------RYIS--KRDIENDEEIRQTSVHQRNCRFADENILDVHK--------FYSY 290

  Fly   360 PNCITRCRIRSIIALCRCLPFQMPLQLVENLDGVVYCTLGHVSCLNQ-------YIFKWRNILTE 417
            ..|..:||....:.||.|.....|     |......|.:..:.|||:       .|.||..:...
  Fly   291 SACTVQCRKDRQMELCNCSSHLSP-----NSPDWQLCNMEGLECLNRNYEDLSVIIAKWSKLRGR 350

  Fly   418 RHIVNGLEREIEEALYCPQCLPSCRDVQYEVSMSALPIDNYLATLKLDENNETEFGTDISVLRVY 482
            :.:|            | .|||||.:|.             :.|:.  ::.|...|:..::.|:.
  Fly   351 KGLV------------C-DCLPSCTEVD-------------ITTVY--DSKENMAGSQNAISRIE 387

  Fly   483 FG--DPHAQYYIRLLNNTWFEVFSTIGNIMSIFVGFSMVAIFEILFFVT 529
            .|  :...:.|.|.|.....::..:||....:|||.|:::..||.:::|
  Fly   388 VGLIELPTERYKRNLVRGKLDLVVSIGGTTGLFVGASLLSFVEIFYYIT 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:279230	107/497 (22%)
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	107/499 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	5	4.920