Protein Alignment ppk22 and asic-2

DIOPT Version :10

• Sequence 1: NP_733051.2
• Gene: ppk22 / 318593
• FlyBaseID: FBgn0051105
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 109/585 - (18%)
• Similarity: 192/585 - (32%)
• Gaps: 202/585 - (34%)

  Fly    66 RLIWLLVHMATTVSLIVVLSLTWEQF--VAQSF---VTNLKDPLFPVENVPFPAVSICPNNRISR 125
            |:.|:      .:.|.|:....:|.:  :|:.|   .|...:.||  |...||.|::|..|
 Worm    34 RIFWI------AIFLFVLGMFAYELYILIAKFFSYPATVNTEILF--EKQIFPVVTVCNMN---- 86

  Fly   126 QAVIQYAEELRLNSPVIRPVEYFLERLRFFREFYTHVGVVVDTDDFITFQTF-LDVFGTW--NNE 187
                              |.:|.:.:   ....::.|..::.|....|..|| .|.:|.:  |:|
 Worm    87 ------------------PYKYSVVK---SNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDE 130

  Fly   188 TF-----------------FDTRRIMKMLTPRCQGFVLKCTVANVEVPCFSKDAFQDSLTMYGPC 235
            |:                 .||.::..:.|  ....:..|:.|.  :||...|..:....:||.|
 Worm   131 TYDLDSRAADALVLEANLISDTAKVPALYT--YADLIQDCSFAG--IPCSESDFTKFIDPVYGAC 191

  Fly   236 CTFNMENKLKKRHFKNRLASSE---LGLKVVL------NDSHVDYF-----------------AP 274
            .:||.:..|      |...|.|   .|||::|      .:.:.|..                 :|
 Worm   192 YSFNEDASL------NYSVSREGIQFGLKLMLTVTQTKTNGNTDSLPTTKLAGARIGVNSRGSSP 250

  Fly   275 ILNTNGYIVMIHNAENYASVYSSNVLEMFPGQGEDSYIAVCARVVDTDDSLKSFSPFSRRCYFEY 339
            .|::||    |.....|.|..|.::.:..  :.:..|.....|..|:.|..|.|
 Worm   251 GLDSNG----IDAGVGYESAVSVSLTQNV--RAKKPYGTCVDREPDSSDYYKDF----------- 298

  Fly   340 EAQNPIHEQLMNTYSLSYTFPNCITRCRIRSIIALCRCL--------------PFQMPLQLVENL 390
                            .||...|...|:.|..||.|:|.              |.:..|..::.|
 Worm   299 ----------------IYTLETCFNGCKQRDTIAKCQCANPRLALGSTDTACQPIKADLDCLQTL 347

  Fly   391 DGVVYCTLGHVSCLNQYIFKWRNILTERHIVNGLEREIEEALYCPQCLPSCRDVQY--EVSMSAL 453
            .|            ||               ......|:..:.| .|.|.|.:..|  .||::..
 Worm   348 KG------------NQ---------------TSSTPNIDLLVEC-NCNPPCDESTYTPTVSLAQF 384

  Fly   454 PIDN-YLAT-------------LKLDENNETE--FGTDISVLRVYFGDPHAQYYIRLLNNTWFEV 502
            |..: |:||             .|....::.:  :..:..:::|:......:.|......|...|
 Worm   385 PSTSYYVATSSTAGVGSCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNV 449

  Fly   503 FSTIGNIMSIFVGFSMVAIFEI--------LFFVTKYIYKGCNRMV---EQNIMDRKAKELETKK 556
            .:.:|....:::|.|::::.|:        .|.||    .|..:|.   ::...|.:.|::|..|
 Worm   450 INDLGGQAGLWLGLSVISVVEMTGLMLVMGAFCVT----GGAIKMAPDDDEIENDHRIKDVEDVK 510

  Fly   557  556
             Worm   511  510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:459966	100/551 (18%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	100/543 (18%)