Protein Alignment ppk22 and Asic3

DIOPT Version :9

• Sequence 1: NP_733051.2
• Gene: ppk22 / 318593
• FlyBaseID: FBgn0051105
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 559
• Identity: 107/559 - (19%)
• Similarity: 193/559 - (34%)
• Gaps: 153/559 - (27%)

  Fly    40 DMADLVRNISLQGYNKLLSP-DLTLGQRLIW---LLVHMATTVSLIVVLSLTWEQFVAQSFVTNL 100
            |:.....:.::.|...:..| .||| :|.:|   :|:.:|..:..:......:.:|..::.:...
Mouse    17 DIRVFANSCTMHGLGHIFGPGGLTL-RRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDER 80

  Fly   101 KDPLFPVENVPFPAVSICPNNRISRQAV----IQYAEELRLNSPVIRPVEY--FLERLRFFREFY 159
            :.     ..:.||||::|..|.:.|..:    :.:|....|.   :.|.|:  :|..|
Mouse    81 ES-----HQLTFPAVTLCNINPLRRSRLTPNDLHWAGTALLG---LDPAEHAAYLRAL------- 130

  Fly   160 THVGVVVDTDDFITFQTFLDVFGTWNNETFFDTRRIMKMLTPRCQGFVLKCTVANVEVPCFSKDA 224
               |.......|:...|             ||..::........:..:|.|....  .|| ..:.
Mouse   131 ---GQPPAPPGFMPSPT-------------FDMAQLYARAGHSLEDMLLDCRYRG--QPC-GPEN 176

  Fly   225 FQDSLTMYGPCCTFNMENKLKKRHFKNRLASSEL----------GLKVVLNDSHVDYFAPILNTN 279
            |....|..|.|.|||           :....:||          ||:::|:....:|. ||....
Mouse   177 FTVIFTRMGQCYTFN-----------SGAQGAELLTTPKGGAGNGLEIMLDVQQEEYL-PIWKDM 229

  Fly   280 -------GYIVMIHNAENYASVYSSNVLEMFPGQGEDSYIAVCARVVDTDDSLKSFSPFSRRCY- 336
                   |..|.||..|...::   :.|......|..:::: |.:     ..|....|....|.
Mouse   230 EETPFEVGIRVQIHGQEEPPAI---DQLGFGAAPGHQTFVS-CQQ-----QQLSFLPPPWGDCNT 285

  Fly   337 ------FEYEAQNPIHEQLMNTYSLSYTFPNCITRCRIRSIIALCRC----LP------------ 379
                  |:.|..:|:...   :.|..|:...|...|..|.:...|.|    :|
Mouse   286 ASVDPDFDPEPSDPLGSP---SSSPPYSLIGCRLACESRYVARKCGCRMMHMPGNSPVCSPQQYK 347

  Fly   380 ------------FQMPLQLVENLDGVVYCTLGHVSCLNQYIFKWRNILTERHIVNGLEREIEEAL 432
                        |.:|:.:..::|   :..||.|.           :.......:.:.|  ::..
Mouse   348 DCASPALGKAHLFSLPVPIHSDID---HNPLGQVL-----------LFLALRPADAMLR--KDTC 396

  Fly   433 YCPQCLPSCRDVQY--EVSMSALP---IDNYLATLKLDENNETEFGTDISVLRVYFGDPHAQYYI 492
            .||.   .|...:|  |:||..:|   ...|||  :....:||....::.||.::|   .|..|.
Mouse   397 VCPN---PCATTRYAKELSMVRIPSRASARYLA--RKYNRSETYITENVLVLDIFF---EALNYE 453

  Fly   493 RLLNNTWFEVFSTIGNI---MSIFVGFSMVAIFEILFFV 528
            .:.....:||...:|:|   |.:|:|.|::.|.|||.::
Mouse   454 AVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:279230	106/550 (19%)
Asic3	XP_006535700.1	ASC	21..546	CDD:383197	106/555 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842179
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850