Protein Alignment ppk22 and scnn1d

DIOPT Version :10

• Sequence 1: NP_733051.2
• Gene: ppk22 / 318593
• FlyBaseID: FBgn0051105
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_031762206.1
• Gene: scnn1d / 100496702
• XenbaseID: XB-GENE-991876
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 123/653 - (18%)
• Similarity: 222/653 - (33%)
• Gaps: 186/653 - (28%)

  Fly    24 NSKGKRKESLGSAFCLDMADLVR----NISLQGYNKLLSPDLTLGQRLIWLLVHMATTVSLIVVL 84
            :::.::||.| ..|.....|:::    |.::.|..:|........:...||:::       .|..
 Frog     3 STEKEKKEGL-IEFYDSFEDMLKFFCDNTTIHGTVRLNCSRENKMKTTFWLVLY-------FVAF 59

  Fly    85 SLTWEQFVAQSFVTNLKDP--LFPVENV--------PFPAVSICPNNRISRQAVIQYAEELRLNS 139
            ::.:.||      ..|.|.  .:|...:        .||||:||..|......|..|..:|   .
 Frog    60 AMMYWQF------GQLTDQYWAYPTNTIIGLQSKGKIFPAVTICNLNPYRFDQVNMYINQL---D 115

  Fly   140 PVIRPVEYFLERLRFFREFYTHVGVVVDTDDFITFQTFLDVFGTWNNETFFDTRRIMKMLTPRCQ 204
            .:.:...|.|....:  |.......|||..|.:.     :|.|.:|.....|...:::.|.....
 Frog   116 QLAKETLYLLYEYEY--EVPESPQQVVDLQDLLN-----NVTGQFNGNFILDQSIVLQKLQENGS 173

  Fly   205 G--------------------------------------------------------------FV 207
            |                                                              ::
 Frog   174 GPALPGQKKFKVGFKLCNSSGDCYYKWFWSGFDAVHEWYKFHYINIMSNIPAVLNIANNFSRDYI 238

  Fly   208 LKCTVANVEVPCFSKDAFQDSLTMYGPCCTFNMENKLKKRHFKNRLASSELGLKVVLNDSHVDYF 272
            |.|...  |:||..::.......:||.|.|.|  |..|:..:.:.....:.||.:|:.....|..
 Frog   239 LTCHFN--EMPCDEREYVHFHHPIYGNCFTIN--NHWKENSWYSSRPGKQYGLSIVVKTDLHDNM 299

  Fly   273 APILNTNGYIVMIHNAENYASVYSSNVLEMFPGQGEDSYIAVCARVVDTDDSLKSFSPFSRRCYF 337
            ..:....|..:|||| .|...:......::.||. |:|.      .|..:::::....:| :|..
 Frog   300 PLLSQAAGARIMIHN-PNQPPLVEHQGFDIRPGT-ENSI------SVKQEEAIRLGGKYS-QCTS 355

  Fly   338 EYEAQNPIHEQLMNTYSLSYTFPNCITRCRIRSIIALCRCLPFQMPLQLVENLDGVVYCTL---- 398
            :   .:.:..:::  |:.|||...|:..|....:|.:|.|..:..||.     .|:.||..
 Frog   356 D---GSDLGIKIL--YNTSYTMQACLNSCFQYKMIEVCGCGYYFYPLP-----PGMEYCNYNKHP 410

  Fly   399 --GHVSCLNQYIFKWRNILTERHIVNGLEREIEEALYC-PQCLPSCRDVQYEVSMSAL----PID 456
              |:  |..|.                .|:.::..|.| .||...|:..:|.:|....    |:.
 Frog   411 DWGY--CFYQL----------------YEKMLDHTLICFTQCPKQCKQTEYHLSAGTAKWPSPVS 457

  Fly   457 NYLATLKLDEN-NETEFGTDISVLRVYFGDPHAQYYIRLLNNTWFEVFSTIGNIMSIFVGFSMVA 520
            .....|.|.|. |.|...:|||.:.||:.:...:......:.:...:.|::|.:.|.:.|.|:::
 Frog   458 KAKKLLSLQERYNSTSKRSDISKINVYYEELSYRSVEETPSVSVTMLLSSMGGLWSWWFGSSVLS 522

  Fly   521 IFEI-------LFFVTKYIYKGCNRMVEQN----------------IMDRKA----------KEL 552
            :.||       :..|...||:...:..::|                .:|.||          |||
 Frog   523 VAEIAELVLDTVAMVIIVIYQWKKQRAKRNDGTIGTDAASNICPVPYIDSKAFSSPQTGPPGKEL 587

  Fly   553 ETK 555
            |:|
 Frog   588 ESK 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:459966	106/575 (18%)
scnn1d	XP_031762206.1	ENaC	18..583	CDD:273304	114/628 (18%)