Protein Alignment ppk22 and scnn1g

DIOPT Version :10

• Sequence 1: NP_733051.2
• Gene: ppk22 / 318593
• FlyBaseID: FBgn0051105
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_031749443.1
• Gene: scnn1g / 100487822
• XenbaseID: XB-GENE-980897
• Length: 672
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 127/589 - (21%)
• Similarity: 212/589 - (35%)
• Gaps: 156/589 - (26%)

  Fly    37 FCLDMADLVRNISLQGYNKLLSPDLTLGQRLIWLLVHMATTVSLI----VVLSLTWEQFVAQSFV 97
            :||       |.:..|..:::.....| :|.||:::.:. .|:||    .:|.:::....|...|
 Frog    43 YCL-------NTNTHGCRRIVVSKGRL-RRWIWIVLTLC-AVALIFWQCALLLMSYYSVSASITV 98

  Fly    98 TNLKDPLFPVENVPFPAVSICPNNRISRQAVIQYAEEL-RLNSPVIRPVEYFLERL-RFFREFYT 160
            |        .:.:.||||:||..|..|...:......| |..|..::.:..|.|.| |..|:
 Frog    99 T--------FQKLVFPAVTICNLNPYSYSKIKDRLSALERETSQTLKNIYGFTEPLVRSKRD--- 152

  Fly   161 HVGVVVD---TDDFITFQTFLDVFGTWNNE-------TFFDTRRIMKMLTPRCQ---------GF 206
               |.||   ||.||.......:.....|:       |...||...|::....:         ||
 Frog   153 ---VEVDENSTDIFIKQIPLYRLESVQGNQLVVSDLKTKKRTRMSAKVIHRDAESVQDPGNMVGF 214

  Fly   207 VL-------KCTV------------------ANV-------------------EVPCF----SKD 223
            .|       .||:                  .||                   .|.||    |.|
 Frog   215 KLCDPNNSSDCTIFTFSSGVNAIQEWYRLHYTNVLAKISMEDKIAMGYKADELIVTCFFDGLSCD 279

  Fly   224 AFQDSL---TMYGPCCTFNMENKLKKRHFKNRLASS----ELGLKVVLNDSHVDYFAPILNT-NG 280
            |...:|   .:||.|.|||...:      .|.|.||    |.||||||.... |.:.|.|:| .|
 Frog   280 ARNFTLFHHPLYGNCYTFNSAER------GNLLVSSMGGAEYGLKVVLYIDE-DEYNPYLSTAAG 337

  Fly   281 YIVMIHNAENYASVYSSNVLEMFPGQGEDSYIAVCARV-VDTDDSLKSFSPFSRRCYFEYEAQNP 344
            ..:::|:.:.|..:         ...|.:...|....: :...:|.|...|:| .|     ..:.
 Frog   338 AKILVHDQDEYPFI---------EDLGTELETATETSIGMQLTESTKLSDPYS-DC-----TMDG 387

  Fly   345 IHEQLMNTYSLSYTFPNCITRCRIRSIIALCRCLPFQMPLQLVENLDGVVYCTLGHVSCLNQYIF 409
            ....:.|.||..||...|:..|..|.::..|.|..:..||.     :|..||............|
 Frog   388 SDVSVENLYSKKYTLQICLNSCFQREMVRTCGCAHYDQPLP-----NGAKYCNYEEYPSWIYCYF 447

  Fly   410 KWRNILTERHIVNGLEREIEEALYCPQ-CLPSCRDVQYEVSMS-----ALPIDNYLATL---KLD 465
            |.            .::.::|.|.|.. |..||...::.::.|     :|..:.::..:   :|.
 Frog   448 KL------------YKQFVQEELGCQSACRESCSFKEWTLTRSLAKWPSLNSEQWMLRVLSWELG 500

  Fly   466 EN-NETEFGTDISVLRVYFGDPHAQYYIRLLNNTWFEVFSTIGNIMSIFVGFSMVAIFEI--LFF 527
            |. |:.....|::.|.:::.|.:::............:.|..|..:.:::..||:.:.||  :||
 Frog   501 EKLNKNLTKNDLANLNIFYQDLNSRSISESPTYNIVTLLSNFGGQLGLWMSCSMICVLEIVEVFF 565

  Fly   528 VTKY 531
            :..:
 Frog   566 IDSF 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk22	NP_733051.2	ASC	46..527	CDD:459966	123/574 (21%)
scnn1g	XP_031749443.1	ENaC	35..651	CDD:273304	127/589 (22%)