DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and LIPF

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001185758.1	Gene:	LIPF / 8513	HGNCID:	6622	Length:	408	Species:	Homo sapiens

Alignment Length:	384	Identity:	128/384 - (33%)
Similarity:	206/384 - (53%)	Gaps:	21/384 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGL 106
            :|:..::::      ..|...|||.|.:.|.||||||:.:.||||.........:||:.|:||||
Human    38 SPEVTMNIS------QMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGL 96

  Fly   107 FASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIA 171
            .||:..|.|..|::.|.|:|:||||||||||:|||.:::.:........:||.||:.|:..:|:.
Human    97 LASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLP 161

  Fly   172 AAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVN 236
            |.||:.:. :.||.|  :||:|||||||:.|:..|:.|....:|||.:.|||||.:.:... ::|
Human   162 ATIDFIVK-KTGQKQ--LHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKS-LIN 222

  Fly   237 TLS--PYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTNSTA 299
            .|.  |    .:::..:|..:.|.|||.|...|...||..| ::...||::..........|...
Human   223 KLRFVP----QSLFKFIFGDKIFYPHNFFDQFLATEVCSRE-MLNLLCSNALFIICGFDSKNFNT 282

  Fly   300 SALTSGVM--PAGVSTDQILHYMQEHQSGHFRQFDFGTK-KNMKVYGTEAPEDYPTELITAEMHL 361
            |.|...:.  |||.|...:.|:.|..:||.|:.:|:|:. :|...|....|..|....:...:.:
Human   283 SRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAV 347

  Fly   362 WYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNE 420
            |....|.:|..:||..:...||| :::|.|.|.::|:||....:..|.:.:.||::::|
Human   348 WNGGKDLLADPQDVGLLLPKLPN-LIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISE 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	126/378 (33%)
		Abhydro_lipase	55..117	CDD:282003	27/61 (44%)
		Abhydrolase_5	104..>239	CDD:289465	57/134 (43%)
LIPF	NP_001185758.1	PLN02872	14..400	CDD:215470	125/377 (33%)
		Abhydro_lipase	45..107	CDD:282003	27/67 (40%)
		Abhydrolase_5	88..>211	CDD:289465	56/125 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141741
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.960