DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and Gm8978

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001310180.1	Gene:	Gm8978 / 668106	MGIID:	3647649	Length:	399	Species:	Mus musculus

Alignment Length:	388	Identity:	121/388 - (31%)
Similarity:	200/388 - (51%)	Gaps:	24/388 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGL 106
            ||:::::::      ..|:...||.|.:.|.|:||||:.:.|||:..|..|....:.:.|..|||
Mouse    26 NPESNMNVS------EIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSTAPKMVVFCLHGL 84

  Fly   107 FASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIA 171
            |:::..|.|..||:.|.|:|:||||||||||.||:..:|.|.:..|...:||.||:.|:..:|:.
Mouse    85 FSTAGIWVSNPPDNSLAFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKEFWAFSYDEMIKYDLP 149

  Fly   172 AAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVN 236
            |.|.:.|. :.||.|  |:|.||||||.:.....::..|..:|||.:.::|||..:.::..  ..
Mouse   150 AIIKFILE-KTGQKQ--IYYTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKG--AG 209

  Fly   237 TLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTT----EEGRTNS 297
            .|..|. ....:..:|..:||.|...| ..|...|| ...:|.:.|::...:.|    |:..|:.
Mouse   210 RLPAYF-TPTAFKIVFGEKEFFPTKVF-SRLSQHVC-DIKLVDAGCATVLGSLTGYSPEQFNTSR 271

  Fly   298 TASALTSGVMPAGVSTDQIL-HYMQEHQSGHFRQFDFGTKK-NMKVYGTEAPEDYPTELITAEMH 360
            ....:|..:   |.|:.||| ||.|..:||.|:.:|:|:.. ||:.|....|..|..|.:.....
Mouse   272 IDVYITHSL---GESSIQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTA 333

  Fly   361 LWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEYEG 423
            ::....|.::..|||..:...:.|...|.:... :.|:||.:....|:.:::.|:.||.:|:|
Mouse   334 MFSGLKDFLSNPEDVANLVPKISNLTYHKIISD-FSHLDFIMGLNARKEVSEEILTILRKYDG 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	117/379 (31%)
		Abhydro_lipase	55..117	CDD:282003	22/61 (36%)
		Abhydrolase_5	104..>239	CDD:289465	53/134 (40%)
Gm8978	NP_001310180.1	PLN02872	17..391	CDD:215470	118/382 (31%)
		Abhydro_lipase	33..94	CDD:282003	21/66 (32%)
		Abhydrolase_5	77..242	CDD:289465	62/171 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831774
Domainoid	1	1.000	55	1.000	Domainoid score	I11049
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.960