DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and lipa

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	406	Identity:	137/406 - (33%)
Similarity:	200/406 - (49%)	Gaps:	46/406 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FSNDPAEVPNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNI 90
            :|.||....|..||                   |...|||.|.:.|.||||||:|:.|||  |.:
Frog    39 YSADPEATMNISEL-------------------IRYRGYPSEEYEVLTEDGYILSVNRIP--HGV 82

  Fly    91 QNQQE-KRPIAFIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSH 154
            :...| .:|:.|:||||.|....|.:...::.|.|:|:|||||||:||:|||.:|:.|.|.....
Frog    83 KYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQ 147

  Fly   155 PDFWRFSWHEIGYFDIAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAH 219
            .:||.||:.|:...|:.|.:|: ::.:.||:|  |.|:|||||||:.|:..||.|:...|||...
Frog   148 EEFWAFSYDELAKKDLPAVVDF-ITKKTGQEQ--IFYVGHSQGTTIAFIAFSSLPQLAKKIKMYF 209

  Fly   220 MLAPVAFMDHMDDVM--VNTLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFC 282
            .|||||.:......:  :..|..:|     ...||...||||....:..|....| ..:|....|
Frog   210 GLAPVATVKFSKSPLAKLGVLPEFL-----IEELFGKGEFLPQTYLITWLATHFC-THAIADELC 268

  Fly   283 -------SSSNETTTEEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTKKNMK 340
                   |..||......|.|     :.|...|||.|...:||:.|..:||..:.||||||.||.
Frog   269 GNIFFLLSGFNEKNLNMSRVN-----VYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMI 328

  Fly   341 VYGTEAPEDYPTELITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWE 405
            .|....|..|....:|....||...:|.:|..:||..:...:.| :::|.|.|.|:|:||....:
Frog   329 HYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQVSN-LVYHKEIPDWEHLDFIWGLD 392

  Fly   406 VRQYINDPIVAILNEY 421
            ..:.:.:.|:|::.::
Frog   393 APERMYNEIIAMMKKF 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	130/383 (34%)
		Abhydro_lipase	55..117	CDD:282003	26/62 (42%)
		Abhydrolase_5	104..>239	CDD:289465	55/136 (40%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	28/81 (35%)
		PLN02872	50..409	CDD:215470	133/395 (34%)
		Abhydrolase_5	91..>229	CDD:289465	58/140 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.030