DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and Lipf

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_059037.1	Gene:	Lipf / 50682	RGDID:	708441	Length:	395	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	128/391 - (32%)
Similarity:	211/391 - (53%)	Gaps:	35/391 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGL 106
            ||:|:::::      ..|...|||.:.:.|.||||||:.::|||:..|......|||:.::||||
  Rat    27 NPEANMNIS------QMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGL 85

  Fly   107 FASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIA 171
            .||:..|.:..|::.|.|:|:||||||||||:|||.:|:.:........:||.||:.|:..:|:.
  Rat    86 IASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLP 150

  Fly   172 AAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVN 236
            |.|::.:. :.||::  |||:|||||||:.|:..|:.|....||||.:.|||||.:.:
  Rat   151 ATINFIVQ-KTGQEK--IHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKY------- 205

  Fly   237 TLSPYLGFNNI----YSTLFCSQEFLPHNDFVLALMYSVC-------LPESIVYSFCSSSNETTT 290
            |.||....:.|    :..:|..:.||||..|...|...||       |..:.::.||.      .
  Rat   206 TQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCG------F 264

  Fly   291 EEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGT-KKNMKVYGTEAPEDYPTEL 354
            ::...|.:...:..|..|||.|....||:.|..:||.|:.|::|: .:||..|..:.|.:|....
  Rat   265 DKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSA 329

  Fly   355 ITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILN 419
            :|..:.:|...:|.:|..:||..:...|.| ::.|.|...::|:||....:..|.:.:.:::::.
  Rat   330 MTVPVAVWNGGNDILADPQDVAMLLPKLSN-LLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMA 393

  Fly   420 E 420
            |
  Rat   394 E 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	127/385 (33%)
		Abhydro_lipase	55..117	CDD:282003	25/61 (41%)
		Abhydrolase_5	104..>239	CDD:289465	57/134 (43%)
Lipf	NP_059037.1	PLN02872	4..389	CDD:215470	127/384 (33%)
		Abhydro_lipase	34..96	CDD:282003	25/67 (37%)
		Abhydrolase_5	77..>221	CDD:289465	62/153 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960