DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and Lipn

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001178884.1	Gene:	Lipn / 499345	RGDID:	1560354	Length:	398	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	116/389 - (29%)
Similarity:	192/389 - (49%)	Gaps:	17/389 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 FYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIA 100
            |:|...||:..::.:      ..|..:|||.|.:.|||.||||:::.|||:..........||:.
  Rat    23 FFENTVNPEVWMNAS------EIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVV 81

  Fly   101 FIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEI 165
            ::||.|||.:.:|....|:..|.|||:|||||||:||:|||.:|:.|.:...:...||.||:.|:
  Rat    82 YMQHALFADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFDEM 146

  Fly   166 GYFDIAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHM 230
            ..:|:...||:.:: :.||::  :::||||.|||:.|:..|:.||...:||....|.||....:.
  Rat   147 AKYDLPGIIDFIVN-KTGQEK--LYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKYP 208

  Fly   231 DDVMVNTLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRT 295
            ..:..   |.:|...::...:|.::.|...:........:|| .:.::...||..........:.
  Rat   209 TSIFT---SFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVC-NKKLLRPMCSEFMSLWAGFNKK 269

  Fly   296 NSTASALT--SGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTK-KNMKVYGTEAPEDYPTELITA 357
            |...|.|.  ....|.|.|...|||..|.:||..||.:|:|:: :||..|....|..|....:..
  Rat   270 NMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMKV 334

  Fly   358 EMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEY 421
            ...:|....|.:...:||.|:...:.| :.:..:.|.|:|.||....:..|.:...|:.::.||
  Rat   335 PTAIWAGGHDVLVTPQDVARILPQITN-LRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGLMKEY 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	112/376 (30%)
		Abhydro_lipase	55..117	CDD:282003	23/61 (38%)
		Abhydrolase_5	104..>239	CDD:289465	50/134 (37%)
Lipn	NP_001178884.1	Abhydro_lipase	37..97	CDD:282003	23/65 (35%)
Lipn	NP_001178884.1	Abhydrolase_1	79..379	CDD:278959	92/307 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960