DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31091 and Lip4

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001260356.1	Gene:	Lip4 / 34450	FlyBaseID:	FBgn0032264	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	150/395 - (37%)
Similarity:	218/395 - (55%)	Gaps:	31/395 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRP 98
            ||..|     |:||      :|...|:::|||.|.|.:.|:||||::|.||           .||
  Fly    75 PNIQE-----DSHL------NTYSLIKKYGYPAENHTLETDDGYILTLHRI-----------ARP 117

  Fly    99 IA---FIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRF 160
            .|   .:.|||..||..|..:||:.||.:||.|.|||||:.|.|||.||:.|....|.|..||.|
  Fly   118 GATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDF 182

  Fly   161 SWHEIGYFDIAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVA 225
            ::||:|..||.|.:||.|:: .|..|  :|||||||||.|.:::.|.:|||.|||.....|||||
  Fly   183 TFHEMGKHDIPATMDYILNS-TGVSQ--LHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVA 244

  Fly   226 FMDHMDDVMVNTLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTT 290
            |:.|....:||.|:.:....::...|....||||.|:|:......:|...:|....||:....||
  Fly   245 FLKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTT 309

  Fly   291 --EEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTKKNMKVYGTEAPEDYPTE 353
              ::.:.|.|...:..|..|||.||.|:.|:.|.::||.|||:|.|..:|..:|||..|..|..|
  Fly   310 GFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLE 374

  Fly   354 LITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHM-EDPLWDHMDFALNWEVRQYINDPIVAI 417
            .:.|::.|:|..:|.:|..|||..:...|||.|..:: :|..::|:||....:.|:.:.|.::.|
  Fly   375 NVRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEI 439

  Fly   418 LNEYE 422
            :..:|
  Fly   440 MRNHE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	145/379 (38%)
		Abhydro_lipase	55..117	CDD:282003	24/64 (38%)
		Abhydrolase_5	104..>239	CDD:289465	67/134 (50%)
Lip4	NP_001260356.1	PLN02872	88..446	CDD:215470	143/371 (39%)
		Abhydro_lipase	88..139	CDD:282003	23/61 (38%)
		Abhydrolase_5	121..>253	CDD:289465	65/134 (49%)
		Abhydrolase_5	<368..419	CDD:289465	16/50 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439523
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	9.000