DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and Lipk

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_017444545.1	Gene:	Lipk / 294094	RGDID:	1309724	Length:	402	Species:	Rattus norvegicus

Alignment Length:	424	Identity:	128/424 - (30%)
Similarity:	199/424 - (46%)	Gaps:	39/424 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IAVICAFV-GIFVGTVVQSAPFSNDPAEVPNFYELFNNPDAHLSLTNGPDTI---HFIEEHGYPV 66
            :|..|.|: |...|                :..|...||:|::::.    .|   ..|...|||.
  Rat     5 LATCCMFLPGPIYG----------------HMQESITNPEANMNIV----CIFQSEIISYWGYPY 49

  Fly    67 ERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDFWPSLGPDDGLPFLLSDAGY 131
            |||.|.||||||:..:|||:......:...:.:.::||||.||:..|....|::.|.|||:|:||
  Rat    50 ERHDVVTEDGYILGTYRIPHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSGY 114

  Fly   132 DVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAAAIDYTLSTENGQDQKGIHYIGHSQ 196
            ||||||:|||.:|:.|.......|::|.||..|:..:|:.|.|:..|. ::||.|  :.|:||||
  Rat   115 DVWLGNSRGNTWSRKHLRLSPKSPEYWAFSLDEMAKYDLPATINLILE-KSGQKQ--LFYVGHSQ 176

  Fly   197 GTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVM--VNTLSPYLGFNNIYSTLFCSQEFLP 259
            |||:.|:..|:.||...||:....||||..:.:....|  :.|||     ......||..:.|..
  Rat   177 GTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQSPMKKLTTLS-----RKAVKILFGDKMFST 236

  Fly   260 HNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTNSTASALT--SGVMPAGVSTDQILHYMQE 322
            |......:...|| ...:....||:...:.:.....|...|.|.  ....|||.|...:||:.|.
  Rat   237 HTWLEQFIATKVC-NRKLFRQLCSNFLFSLSGFDPQNLNMSRLDVYMAQSPAGTSVQNMLHWAQA 300

  Fly   323 HQSGHFRQFDFGT-KKNMKVYGTEAPEDYPTELITAEMHLWYSDSDEMAAVEDVLRVAETLPNKV 386
            ..||..:.||:|. .:||..:....|..|....:.....:|....|.:|..:|...:...:.| :
  Rat   301 VNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGRDVVADEKDTKNLLPKVAN-L 364

  Fly   387 MHHMEDPLWDHMDFALNWEVRQYINDPIVAILNE 420
            :::.|.|.::||||.|..:..|.:...::.::.|
  Rat   365 IYYKEIPHYNHMDFYLGQDAPQEVYRDLITMMEE 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	121/381 (32%)
		Abhydro_lipase	55..117	CDD:282003	25/64 (39%)
		Abhydrolase_5	104..>239	CDD:289465	57/136 (42%)
Lipk	XP_017444545.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960