DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31091 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	452	Identity:	123/452 - (27%)
Similarity:	208/452 - (46%)	Gaps:	65/452 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HIAVICAFVGIFVGTVVQSAPFSNDPAEVP---------------NFYELFNNPDAHLSLTNGPD 54
            ::.||.||||::...|.:...:.     :|               ::|......|..........
pombe    14 YVGVIAAFVGVYTELVARIFIYM-----IPERVREWFRVRIIVLYHYYISSKTTDGMTDAVQKCR 73

  Fly    55 TIHFI-EEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDFWPSLGP 118
            .|:.| |..||.||.|.|.|:|.:|:.|.||.:.   :..|.||.:.:..|||..:|:.|.::..
pombe    74 NIYEICEAFGYRVEEHLVRTQDNFILCLHRITHP---KQSQHKREVVYCHHGLMTNSELWVAVNE 135

  Fly   119 DD-GLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAAAIDYTLSTEN 182
            .: .|||:|.::||||||||.|||:||:.|.:......:||.||..::..|||...:||.| .|.
pombe   136 SERSLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYIL-RET 199

  Fly   183 GQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIK----TAHMLAPVAFMDHMDDVMVNTLSPYLG 243
            |:::  ::|||.||||......||..|:.|||:.    .|...||..|.::..|.:|. ::|.:.
pombe   200 GREK--LNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFSNYFVDYIVK-VNPKIM 261

  Fly   244 FNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTNSTASALTSGV-- 306
            ::     ||..:..||...|    ..::|.| .|.......|.:.......:|.:.:....|.
pombe   262 YH-----LFGRRCLLPSVTF----WQNICYP-PIFVKIVDVSLKILFNWDLSNISLNQKLCGYAH 316

  Fly   307 MPAGVSTDQILHYMQEHQSGHFRQFDFGTKKNMKV---YGT---EAPEDYPTELITAEMHLWYSD 365
            :.:..|...::|::|..::..|:.:|    .:|.:   ||:   :.|. :||..|...|.:.:..
pombe   317 LYSFSSVKSVVHWLQIIKNCTFQLYD----DDMALLAGYGSRHYQVPL-FPTNNIKCPMLILWGG 376

  Fly   366 SDEMAAVEDVLRVAETLPNKVMHHMEDPL--WDHMDFALNWEVRQYINDPIVAILNEYE-GK 424
            .|.:..:| |:|.|  ||   .|..|..:  ::|:||....:|::.:...::..|..:. ||
pombe   377 KDTLINME-VMRTA--LP---PHAKEVSIAHYEHLDFLWGQDVKEEVFPVVIDALKHHSLGK 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	111/389 (29%)
		Abhydro_lipase	55..117	CDD:282003	23/62 (37%)
		Abhydrolase_5	104..>239	CDD:289465	54/139 (39%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	22/58 (38%)
		Abhydrolase_1	116..410	CDD:278959	91/318 (29%)
		Abhydrolase	<171..>242	CDD:304388	26/73 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	8	7.970