DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31091 and LOC100360690

DIOPT Version :9

Sequence 1:	NP_001247307.1	Gene:	CG31091 / 318591	FlyBaseID:	FBgn0051091	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_006231366.1	Gene:	LOC100360690 / 100360690	RGDID:	2321667	Length:	399	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	117/393 - (29%)
Similarity:	196/393 - (49%)	Gaps:	40/393 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPY--SHNIQNQQEKRPIAFIQH 104
            ||:|:::::      ..|...||..|.|.|.||||||:.:||||:  :.|..:...:||:.::.|
  Rat    27 NPEANMNVS------QIISYWGYESEEHEVMTEDGYILLIFRIPHGKNENKSSHNTRRPVVYLHH 85

  Fly   105 GLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFD 169
            ||..|:|:|....|.:.|.|||:|||::|||||:||...::.|........:||.||::|...:|
  Rat    86 GLTVSADYWILDPPSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKEFWDFSFNEQIEYD 150

  Fly   170 IAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDV- 233
            :.|.| |.:..|..|.|  |:|||||||..:.:...::.|:...|||....|.||....::..|
  Rat   151 LPAII-YFILNETRQTQ--IYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVVITKYLTGVF 212

  Fly   234 ---------MVNTLSPYLGFNNIYSTLFCSQ--EFLPHNDFVLALMYSVCLPESIVYSFCSSSNE 287
                     ::.|:   .|..:|:|....:.  .||.|.:.:.....|:.:   :::.:
  Rat   213 RTIAYIHPTVIKTM---FGEKDIFSKSNANDILRFLCHREQIATACTSLLI---VLFGY------ 265

  Fly   288 TTTEEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTKK-NMKVYGTEAPEDYP 351
               ..|..|.:...:.|..:|||.|...|||:.|..:||.|:.:|:|::. |:..|....|..|.
  Rat   266 ---NPGNLNESRIDVYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYN 327

  Fly   352 TELITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVA 416
            .|.:.....:|..:.|.:...:||..:|...|| :::|.:.|.::||||.|..:....:...|:.
  Rat   328 IEDMKVRTAMWSGERDLLGDPKDVKNLAAKTPN-LIYHKKIPHYNHMDFILGKDAVVQVYRKIIE 391

  Fly   417 ILN 419
            .:|
  Rat   392 FIN 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31091	NP_001247307.1	PLN02872	42..416	CDD:215470	116/388 (30%)
		Abhydro_lipase	55..117	CDD:282003	25/63 (40%)
		Abhydrolase_5	104..>239	CDD:289465	51/144 (35%)
LOC100360690	XP_006231366.1	Abhydro_lipase	34..96	CDD:282003	25/67 (37%)
		Abhydrolase_1	79..378	CDD:278959	93/317 (29%)
		Abhydrolase_5	79..245	CDD:289465	55/171 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335481
Domainoid	1	1.000	64	1.000	Domainoid score	I9870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.960