Protein Alignment SmydA-9 and smyd4

DIOPT Version :10

• Sequence 1: NP_572539.2
• Gene: SmydA-9 / 31859
• FlyBaseID: FBgn0030102
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: XP_012812690.1
• Gene: smyd4 / 779741
• XenbaseID: XB-GENE-945037
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 114/581 - (19%)
• Similarity: 192/581 - (33%)
• Gaps: 186/581 - (32%)

  Fly     4 PKR-----TSELLDLHLAPFKDKDP-------AWEIGVSKIAGRGVVATRSLKRGEIIFRDSPLL 56
            ||:     |..|.::.|    |::|       |..:......||.::|::::::||::..:....
 Frog   212 PKKEPQTSTERLKEMAL----DRNPHITNASCALHLNFDTRKGRHLLASQNIEQGEVLIWEEAFA 272

  Fly    57 IGLAAHE---------EDSLNACS----VCLKMLPDTRFMCRQGCGLPVCSLCAKKKQHKSDCDL 108
            ..:....         :..:.||.    .||.         |....|| |..|:..:....:| :
 Frog   273 SVIIPERKQWRKEIKWDTRITACDHYCHYCLN---------RVIASLP-CQYCSFARYCSQEC-M 326

  Fly   109 FKSWGPN---EPDVANSVI---------IRLLCVA--RAINLSKEQRDLIYCLQANLDNNHRTEV 159
            .|:|...   |..:.:.::         :|.:.||  |..:.|.||       ..:.|...:|:|
 Frog   327 DKAWRSYHYIECSMGDLLLALGMFCHTALRAVLVAGCRLFSQSLEQ-------TGSADATDKTKV 384

  Fly   160 RNAAKCF------------------KNFPTD-------------KKLIEIMNR------------ 181
            .|:...:                  :|.|.:             |||..||.:
 Frog   385 CNSKNTYHEKYCSSYQSVVNLLPHTENHPAERKFLCGLTAAALYKKLCLIMAKDLVSSTSQTEKS 449

  Fly   182 ----------------------------------TVAVLRTNGFDKTTDRTNDNQEFNY-RALYP 211
                                              .|..|:.|..:.:......|:.... .|::|
 Frog   450 LTKESGTIEDWSSVRQFLGPTVLRHMLQLYCNAQAVTALQENEDESSLSLVKSNKSIRLATAVFP 514

  Fly   212 LFGVVNHDCIPNAYYTFEEKTNNMI-VRAAVDIPEGFEVTTTY--TKLFTGNIARHLFLKMKKSF 273
            :..::||.|.||...:|   |...: |||...|....|||..|  .||......|...||.:..|
 Frog   515 VLSLLNHSCDPNTTVSF---TGRFVTVRANRPIRRDEEVTHCYGPHKLRMDVAERQQLLKDQYFF 576

  Fly   274 TCKCSRCSDPTEKGAFISG---------------LYCRDTNCTGLV-VPEITGLPHPNWNCLVCK 322
            .|:|..|::.. ||....|               |||....||... ..::|..         ..
 Frog   577 VCQCKACTEEL-KGKKTHGFFCPLCKAQLEGEEALYCTGARCTYTASQTQLTSR---------LN 631

  Fly   323 QKSTHAQMMKSQDFASGAINAKVNSNSLRTLVQYLNEKSDSFIPSSNYVVIDAKMSVLQRLQQGR 387
            |...|.|:.|.|...:...|||:      ||:..|:| ::.|: |.:::::.   .::..|.|..
 Frog   632 QLGNHIQIAKVQLQDNKTDNAKM------TLMSCLSE-AECFL-SQDHLLLG---EIMDHLAQAE 685

  Fly   388 EDCSEELAHNTRLRYSRDITQL---MDKLGLGDSLLRTHLEELLRREEERRAKRLADEAEK 445
            .......|....||.|..|.::   ...:.||..|.:. .:.|....|...|.|...||:|
 Frog   686 ASDGNWKAAAGHLRKSISIVKVHYGSSSMELGHELFKL-AQILFNGFEVPDAMRTIMEAQK 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-9	NP_572539.2	SET	26..>49	CDD:394802	5/22 (23%)
		SET_SMYD	<183..280	CDD:380997	29/100 (29%)
smyd4	XP_012812690.1	TPR repeat	106..134	CDD:276809
		TPR repeat	143..173	CDD:276809
		SET_SMYD4	234..583	CDD:380934	66/369 (18%)
		zf-MYND	299..338	CDD:460312	10/49 (20%)