Protein Alignment SmydA-9 and Smyd1

DIOPT Version :10

• Sequence 1: NP_572539.2
• Gene: SmydA-9 / 31859
• FlyBaseID: FBgn0030102
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_001153599.1
• Gene: Smyd1 / 12180
• MGIID: 104790
• Length: 490
• Species: Mus musculus
• Alignment Length: 541
• Identity: 115/541 - (21%)
• Similarity: 193/541 - (35%)
• Gaps: 152/541 - (28%)

  Fly    26 EIGVSKIAGRGVVATRSLKRGEIIFRDSPL-------LIGLAAH----EEDSLNACSVCLKMLPD 79
            |:..|:..|||:.||:.....::||.:...       ||....|    .::.|:.|..| |....
Mouse    10 EVFTSEGKGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQC-KFAHY 73

  Fly    80 TRFMCRQGCGLPVCSLCAKKKQHKSDCDLFKSWG--PNEPDVANSVIIRLLCVARAI-NLSKEQR 141
            ....|::...|          .||::|...|.:|  |||.       |||  .||.: .:.:|..
Mouse    74 CDRTCQKDAWL----------NHKNECAAIKKYGKVPNEN-------IRL--AARIMWRVEREGT 119

  Fly   142 DLIYCLQANLDN--NH--------RTEVRNAAKCFKNF--PTDKKL-IEIMNRTVAVLRTNGFDK 193
            .|......::|:  ||        :.|:|.....|..:  |..::. ::.::....|:..|||..
Mouse   120 GLTEGCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTL 184

  Fly   194 TTDRTNDNQEFNYRA----LYPLFGVVNHDCIPNAYYTFEEKTNNMI-----------VRAAVDI 243
            :..|       ..:|    ::|..|:|||||.||....|....:..:           :||...|
Mouse   185 SDQR-------GLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKI 242

  Fly   244 PEGFEVTTTYTKLFTGNIARHLFLKMKKSFTCKCSRCSDPTEKGAFISGLYCRDTNCTGLVVPEI 308
            .||.|:|.:|......:..|...||.:..|.|.|..|....:...|::..  .|...:..||.|
Mouse   243 SEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAK--EDPKPSQEVVKE- 304

  Fly   309 TGLPHPNWNCLVCKQKSTHAQMMKSQDFASGAINAKVNSNSLRTLVQYLNEKSDSFIPSSN-YV- 371
                      ::...|.|..::.|::  :.|..:..|.      |.:...||.:.....:| ||
Mouse   305 ----------MIQFSKDTLEKIDKAR--SEGLYHEVVK------LCRECLEKQEPVFADTNLYVL 351

  Fly   372 -VIDAKMSVLQRLQQGREDCSEELAHNTRLRYSRDITQLMDKL------GLGDSLLRT------- 422
             ::.....||..||     ..||.:|     |:|.:.....||      .||.:::|.
Mouse   352 RLLSIASEVLSYLQ-----AYEEASH-----YARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHA 406

  Fly   423 -HLE---------------------------ELLRREEERRAKRLADEAEKQRKLAELQAKAAEA 459
             |:|                           |.:|.:.|...:..........|:.|    ||..
Mouse   407 GHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMRE----AALN 467

  Fly   460 DKLLEVLQKEQSEQSEQAEPA 480
            ::.::|:    :|.|.:..||
Mouse   468 NQPMQVM----AEPSNEPAPA 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-9	NP_572539.2	SET	26..>49	CDD:394802	7/22 (32%)
		SET_SMYD	<183..280	CDD:380997	30/111 (27%)
Smyd1	NP_001153599.1	SET_SMYD1	7..281	CDD:380924	71/297 (24%)
		zf-MYND	52..90	CDD:460312	9/48 (19%)