Protein Alignment SmydA-9 and SMYD5

DIOPT Version :10

• Sequence 1: NP_572539.2
• Gene: SmydA-9 / 31859
• FlyBaseID: FBgn0030102
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_006053.2
• Gene: SMYD5 / 10322
• HGNCID: 16258
• Length: 418
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 72/356 - (20%)
• Similarity: 126/356 - (35%)
• Gaps: 106/356 - (29%)

  Fly    29 VSKIAGRGVVATRSLKRGEIIFRDSPLLIGLAAHEEDSL---NACSVCLKMLPDT-----RFMCR 85
            ||...|:|:.||:.:::||.||.:.||:  .|....::|   .||..||:.|...     |...:
Human    28 VSSAKGKGLFATQLIRKGETIFVERPLV--AAQFLWNALYRYRACDHCLRALEKAEENAQRLTGK 90

  Fly    86 QGCGLPVCSLCAKKKQ-HK-----------SDCDLFKSW--------GPNEPDVANSV------- 123
            .|..||...||..:|. |:           ::|.|..:.        ||::.|..:.:
Human    91 PGQVLPHPELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAW 155

  Fly   124 --------IIRLLCVARAINLSKEQRD-----LIYCLQANLDNNHRTEV---------RNAAKCF 166
                    ...::.:||.:...|:.:|     .::....|...|...|:         :...:..
Human   156 RSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKGQLELL 220

  Fly   167 KNFPTDKKLIEIMNR---------TVAVLRTNG--------------FDKTTDRTNDNQEFN--- 205
            :...|:....|.:::         ..|::.|||              .|....:..|.::.:
Human   221 RRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELKPQDREQLDAFI 285

  Fly   206 ---YR---------------ALYPLFGVVNHDCIPNAYYTFEEKTNNMIVRAAVDIPEGFEVTTT 252
               |:               .|:.|....||.|:|||..:|.|....:.|.|..||..|.|:..:
Human   286 DQLYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPGEEICIS 350

  Fly   253 Y---TKLFTGNIARHLFLKMKKSFTCKCSRC 280
            |   .:......:||..|:....|.|.|.:|
Human   351 YLDCCQRERSRHSRHKILRENYLFVCSCPKC 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-9	NP_572539.2	SET	26..>49	CDD:394802	8/19 (42%)
		SET_SMYD	<183..280	CDD:380997	30/134 (22%)
SMYD5	NP_006053.2	SET_SMYD5	22..384	CDD:380919	72/356 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	385..418