DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31077 and Muc68D

DIOPT Version :9

Sequence 1:	NP_733185.2	Gene:	CG31077 / 318583	FlyBaseID:	FBgn0051077	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_648504.2	Gene:	Muc68D / 39326	FlyBaseID:	FBgn0036203	Length:	1514	Species:	Drosophila melanogaster

Alignment Length:	1045	Identity:	195/1045 - (18%)
Similarity:	314/1045 - (30%)	Gaps:	341/1045 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GDLVRQRCPAGSNFNVISKNCQMSRTGSCASPKEICLEGELQVDSEDCAGYLECLNGGLVKEKC- 176
            |.|..:....|||.:..:::.|.|.|...:|..|..|..|...::.:.:. .|.......:|..
  Fly   617 GPLSTESSTEGSNESSSTESSQDSTTQKSSSSTESPLSTEPSTEANESSS-TESSQDSTTQESSS 680

  Fly   177 ----PIGSYFEPIFKLCQLDENGVCSSSSSECTDGEVRVDPNNCAGYFNCENGRLITKTCPSGTY 237
                |:.:  ||     ..:.|...|:.||:  |...:...::..|..:.|:..
  Fly   681 STEGPLST--EP-----STEANESSSTESSQ--DSTTQESSSSSEGPLSTESST----------- 725

  Fly   238 FEPTYKTCTVDLKGVCVEPPAKCTEGQLKIDPNNCAGYLKCIDGEFVEEKCPGGTYYDFKLETCL 302
             |....:.|...:....:..:..||..|..:|:..|           .|.....:..|...:...
  Fly   726 -EANESSSTESSQDSTTQESSSSTESPLSTEPSTEA-----------NESSSTESSQDSTTQESS 778

  Fly   303 VDTEGVCVTIRKLCIEGLREKDPKDCAAYTQCIRGRVESVMCDSGRYFNVTQGECLADLYEVCLK 367
            ..|||      .|..|...|.:.......:|           ||     .||....:....:..:
  Fly   779 SSTEG------PLSTEPSTEANESSSTESSQ-----------DS-----TTQESSSSSEGPLSTE 821

  Fly   368 SRKEHFRIVEHHQYDESTTPNSYQQTE-------STDADFQ--STDSALQEVTSQNSCIFDLNGA 423
            |..|...........:|||..|...||       ||:|.::  ||:|:....|.::|.  ...|.
  Fly   822 SSTEANESSSTESSQDSTTQESSSSTEDPLSTESSTEATYESSSTESSQDSTTQESSS--STEGP 884

  Fly   424 CVGQSTICTEGKKQRDINNCAGYLKCIDGEFVEEECPESTYYDSNLETCLVDNYGACVTSTSICV 488
            ...:|:  |||..:....               |...:||..:|:..|
  Fly   885 LSTESS--TEGSNESSST---------------ESSQDSTTQESSSST----------------- 915

  Fly   489 EGIVEEDPKDCAGYNQCVRGKVEPLKCAFGRYFNGTQGECLIDLDEVCAKSSQVDYDRDLEQFQY 553
            |..:..:|...|..:.......:   .......:.|:|....:......:||..:..:|....:.
  Fly   916 ESPLSTEPSTEANESSSTESSQD---STTQESSSSTEGPLSTESSTEANESSSTESSQDSTTQES 977

  Fly   554 SQSTSEYLLEYTNTDTTIADFSTESSNADFNRYTDSNSYTDTESTTNDVPTSTEVST--FDLKTT 616
            |.||...|    :|::     |||.||...:..:..:|.|...|::.:.|.|||.||  .:..:|
  Fly   978 SSSTEGPL----STES-----STEGSNESSSTESSQDSTTQESSSSTESPLSTEPSTEANESSST 1033

  Fly   617 DLSLQFTTLDGVDN----LDINTGTCVYNNTLFIEGIREVNPQDCAGYIECFGGVAKE------- 670
            :.|...||.:...:    |...:.|...|.:...|..::...|:.:...|  |.::.|
  Fly  1034 ESSQDSTTQESSSSTEGPLSTESSTEASNESSSTESSQDSTTQESSSSTE--GPLSTESSTEVTQ 1096

  Fly   671 ---------------LKC-------------------DSGRYFNETQRN------CSVDVDEICL 695
                           ..|                   |||...:|...:      |:.|     .
  Fly  1097 EPSPTESLPNSSTQGTPCTTDNPSSLEPSPSTPGNDDDSGNSGSENGNSSTSGSPCTTD-----N 1156

  Fly   696 KSDKTIVLDLQTTTESTP--------------NFTTSVDPFAKCRDGQLRLDPKNCA-------- 738
            .||       ..::.|||              |.:||..|.......    ||::.:
  Fly  1157 PSD-------PESSSSTPGNDDDSGNSGSENGNSSTSGSPCTTDNPS----DPESSSSTPGNDDD 1210

  Fly   739 --------------GFLKCVDGELKEEMCPS-----GFFYNSTSSKCMVDIRATCVTNI------ 778
                          |.....|....:|..||     |...|| ||:...:....|..|.
  Fly  1211 SGNSGSESGITSTTGAPYTTDNPASQEPSPSAPENPGDSGNS-SSESPPEGATPCTPNAPKKSTT 1274

  Fly   779 ---------KYCIEGVR----------------EED-------PN--------NCAGYRQCIRGL 803
                     ||..||.:                :||       ||        :|..|..|:.|.
  Fly  1275 SSYTAHPTPKYTTEGNKAETSTLKSPTGTTPGHQEDRTDCSNMPNGIFLRDFQSCNKYYVCLNGK 1339

  Fly   804 VQNLNCPLGQYFNVAERDC----LMDVHKVCARTEEVYKSDEVQHNDTGPPM-TKPDESCIRDIN 863
            ....:||...:|::..:.|    |:|    |       ..||...|.|..|. |:....|
  Fly  1340 AIAGHCPRNLHFDIKRKVCNFPSLVD----C-------PLDEAPENVTKKPSDTESTPDC----- 1388

  Fly   864 GVCVDPLAKCREGQHKLDPNNCAGYLKCQNGELIEELCPNGFYYDFLMKICLVDRRGICVTNIQI 928
                   ...|.|.:..||.:|:.:..|.||..|...||.|.::|.....|          |..|
  Fly  1389 -------KSLRNGAYVRDPKSCSRFYVCANGRAIPRQCPQGLHFDIKSNFC----------NYPI 1436

  Fly   929 CDEGALEE---DPH---------DCA---------------GYRQCIDGQVENLKCPFGTYFNVP 966
            ..:.:|||   |.|         ||.               .|..|:.|:.....|..|.:|::.
  Fly  1437 LVQCSLEESQADAHGALLAEGVPDCTKVKEDTRFGDVKQHNKYYVCLKGKAVLHYCSPGNWFDLR 1501

  Fly   967 LRDCL 971
            .:.|:
  Fly  1502 SQKCI 1506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31077	NP_733185.2	CBM_14	43..81	CDD:279884
		ChtBD2	<212..245	CDD:214696	3/32 (9%)
		CBM_14	267..308	CDD:279884	6/40 (15%)
		CBM_14	439..472	CDD:279884	4/32 (13%)
		CBM_14	733..769	CDD:279884	12/62 (19%)
		CBM_14	881..914	CDD:279884	11/32 (34%)
Muc68D	NP_648504.2	ChtBD2	21..69	CDD:214696
		PHA03249	1088..>1209	CDD:223023	19/136 (14%)
		CBM_14	1314..1366	CDD:279884	12/55 (22%)
		CBM_14	1388..1440	CDD:279884	17/73 (23%)
		ChtBD2	1459..1505	CDD:214696	8/45 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020