DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31077 and C39D10.7

DIOPT Version :9

Sequence 1:	NP_733185.2	Gene:	CG31077 / 318583	FlyBaseID:	FBgn0051077	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_509334.3	Gene:	C39D10.7 / 181050	WormBaseID:	WBGene00016534	Length:	1171	Species:	Caenorhabditis elegans

Alignment Length:	1145	Identity:	225/1145 - (19%)
Similarity:	347/1145 - (30%)	Gaps:	390/1145 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 CTEGSVAADIDDCASYFQCIDDETVHLNCANGSYFEASNEICVVDEFGVCPTSRRLCFDGDIFED 100
            |.:|.....:...:.|.||:::.....:|..|.||:.....|      ...:|..||..||
Worm    29 CPDGDGLYAVGCSSKYLQCVNNVEYEQSCPEGLYFDRLLARC------ERRSSNHLCATGD---- 83

  Fly   101 INDCMSYVKCIRGDL-VRQRCPAGSNFNVISKNCQMSRTGSCASPKEICLEGELQVDSEDCAGYL 164
                       |..| |||:        .:|.||....:|..|..|.:|.|           .|.
Worm    84 -----------RVTLNVRQK--------AVSINCVGRLSGDYALDKTVCNE-----------NYY 118

  Fly   165 ECLNGGLVKEKCPIGSYFEPIFKLCQLDENGVCSSSSS--------------------------- 202
            :|.||.....|||....:.||.|.|....|  |::|..
Worm   119 QCANGISYMRKCPYQQVYVPILKRCDYHTN--CNASGGVKDQAAAAYASPTYDSDNYIVTTKEFE 181

  Fly   203 ------EC-TDGEVRVDPN-NCAGYF-NCENGRLITKTCPSGTYF-------------------- 238
                  :| ..|::....| .|:.|| .|.||:|..||||....:
Worm   182 NGHNGLDCKVTGDMHFTDNVKCSPYFWQCSNGKLFRKTCPEKLIYVLDQNLCDFPESVKDCPEYN 246

  Fly   239 --EPTYK----TCTVDLKGVCVEPPAKCTEGQLKIDPNNCAGYLKCIDGEFVEEKCPGGTYYDFK 297
              |.:|:    |.:....|...|.|         :||...|.....:...      |..||....
Worm   247 GSETSYRAPKTTTSSSSYGSIAEAP---------VDPTPYAPASAPVYSP------PRTTYVPRS 296

  Fly   298 LETC-------------LVDTEGV-----CVTIR-KLCIEG-LREKDP----KDC-AAYTQCIRG 337
            ....             .|.||..     ..|:| ...:.| .:.:|.    |:| |::..|..|
Worm   297 TSAAPPNPPPQNPTAAPYVPTEATPSPVFSSTVRYNPAVHGDCKNRDGIFGIKECHASFLSCDNG 361

  Fly   338 RVESVMCDSGRYFNVTQGECLADLYEVCLKSRK-EHFRIVEHH--QYDESTTPNSYQQTESTDAD 399
            ....:.|.....|:.....|  :...:||:.|| |...::.:|  .|:|        :......|
Worm   362 VGRVIQCADNLVFDTRVSAC--EFAAICLEPRKPEDVPVLYNHGGAYNE--------RPAEVKVD 416

  Fly   400 FQSTDSALQEVTSQNSCIFDLNGACVGQSTICTEGKKQRDINNCAGYLKCIDGEFVEEECPESTY 464
            |..|...              ||..:.::  ||:           .:..|.||.....:||....
Worm   417 FDCTGKP--------------NGKYIKEA--CTK-----------SFFTCHDGRAFANDCPGDLV 454

  Fly   465 YDSNLETC-LVDNYGACVTSTSICVEGIVEEDPKDCAGYNQCVRGKVEPLKCAFGRYFNGTQGEC 528
            ::....|| ..:|........|...:|  |:.|....||:..|
Worm   455 FNKATGTCDFAENCEKNYMEPSQIYKG--EDTPTTTIGYSSSV---------------------- 495

  Fly   529 LIDLDEVCAKSSQVDYDRDLEQ----------------FQYSQSTSEYLLEYTNTDTTIA--DFS 575
            :....|..|........||.|:                ..|.|..:.|..:...| ||||  |||
Worm   496 VYTTTEQPATKPYTQPPRDTERPSTIYGRPIYTKAPTTVGYEQPKATYTTQAPVT-TTIALDDFS 559

  Fly   576 -----------------------------TESSNADFNRYTDSNSY-TDTESTTNDVPTSTEVST 610
                                         |..:|..||.|.....| |:........||:|...:
Worm   560 CKHLADGNHASGLCKSVFYICANGQVVATTCPANLIFNPYVGECDYSTNVRDCQGYQPTTTPSYS 624

  Fly   611 FDLKTTDLSLQFTTLDG---VDNLDINTGTC-VYNNTLFIEGIREVNPQ---------------D 656
            :...|:....|.:|..|   ::...:..|.. .|.:|:|   ...::|:               |
Worm   625 YPKTTSKPYEQPSTTQGYAPIEYTPVTPGYAPQYTSTIF---TTTLSPKYAAMCAKRDDGNYGFD 686

  Fly   657 CAGY-IECFGGVAKELKCDSGRYFNETQRNCSVDVD-EICLKSDKTI---------VLDLQ---- 706
            |..| |:|:.....:..|.||.|::..|..|.|..: |.|.:...|.         |:..|
Worm   687 CEKYLIKCYNRKTFKFPCPSGLYYSRLQDKCDVKENVEGCPEYKPTTDATPAAEQPVISYQNYGY 751

  Fly   707 ---TTTESTPNFTTSVDPFA----KCRDGQLRLDPKNCAGFLKCVDGELKEEMCPSGFFYNSTSS 764
               ||....|:.||.....|    :..:|...||.::.  ::.|.:.|.....||:|.||:..::
Worm   752 SQSTTKAYNPSVTTPSPQHAAFCERLENGNYGLDCEDY--YISCNNFETTINRCPAGLFYSKLNN 814

  Fly   765 KCMVDIRATCVTNIKYCIEGVREEDPNNCAGYRQCIRGLVQNLNCPLGQYFNVAERDCLMDVHKV 829
            :|            .|      :|...:|..|:            |.......||:.
Worm   815 RC------------DY------KEHVEDCPEYK------------PTPSTTPAAEQP-------- 841

  Fly   830 CARTE-EVYKSDEVQHNDTGPPMTKPDESCIRDINGVCVDPLAK---CR---EGQHKLDPNNCAG 887
             ..|: ..|....:.:..|.|             ..|...||||   |.   :|.:.| |.....
Worm   842 -GTTKYTTYNYPNIDYTSTTP-------------GPVDTTPLAKAFSCSGRPDGIYAL-PYCSQD 891

  Fly   888 YLKCQNGELIEELCPNGFYYDFLMKICLVDRRGICV--TNIQICDEGALEE--DPHDCAG----- 943
            |::|..|..:...|..|.:|:        ::.|:|.  ..:..|..|...:  |.:.|.|
Worm   892 YVQCMQGRSLISSCAPGLFYN--------EKNGMCAYKHTVDTCKIGKGSDIIDSNACFGKSDGY 948

  Fly   944 --------YRQCIDGQVENLKCPFGTYFNVPLRDCLIDVD 975
                    |..|||.|:..:.||....|:.....|:..:|
Worm   949 YSAGCSSYYFSCIDEQIRKMSCPNSLKFSKESEKCVFPID 988

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31077	NP_733185.2	CBM_14	43..81	CDD:279884	8/37 (22%)
		ChtBD2	<212..245	CDD:214696	14/60 (23%)
		CBM_14	267..308	CDD:279884	9/53 (17%)
		CBM_14	439..472	CDD:279884	5/32 (16%)
		CBM_14	733..769	CDD:279884	9/35 (26%)
		CBM_14	881..914	CDD:279884	7/32 (22%)
C39D10.7	NP_509334.3	CBM_14	29..79	CDD:279884	11/55 (20%)
		CBM_14	98..148	CDD:279884	17/60 (28%)
		CBM_14	189..242	CDD:279884	14/52 (27%)
		ChtBD2	337..384	CDD:214696	10/48 (21%)
		CBM_14	419..467	CDD:279884	12/74 (16%)
		CBM_14	560..612	CDD:279884	7/51 (14%)
		CBM_14	675..726	CDD:279884	13/50 (26%)
		CBM_14	774..825	CDD:279884	13/70 (19%)
		CBM_14	875..927	CDD:279884	12/60 (20%)
		CBM_14	941..992	CDD:279884	12/48 (25%)
		CBM_14	1010..1062	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45499
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930