DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31077 and si:ch211-286b4.4

DIOPT Version :9

Sequence 1:	NP_733185.2	Gene:	CG31077 / 318583	FlyBaseID:	FBgn0051077	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	XP_021322239.1	Gene:	si:ch211-286b4.4 / 100005359	ZFINID:	ZDB-GENE-131127-605	Length:	2996	Species:	Danio rerio

Alignment Length:	1204	Identity:	236/1204 - (19%)
Similarity:	320/1204 - (26%)	Gaps:	464/1204 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FCISAWICLMRPSFGSIIKDSVKCTEGSVAADIDDCASYFQCIDDETVH-LNCANGSY--FEASN 74
            || ...|.:.||.|....:.|    .|....|:  |.:.|.|.:....| ..|..|.|  ..|||
Zfish   711 FC-QRGIIMERPCFPGTFQPS----PGQHRCDV--CPARFFCPEHGMTHPFPCQPGYYCPVGASN 768

  Fly    75 E-ICVVDEFG-------------------------VCPT----SRRLCFDGDIFEDIND------ 103
            : .|....||                         |.||    :..|||.|.:....||
Zfish   769 QHPCPPGGFGNRSGLADSSECSQCDPGTYCMGSGNVSPTGPCSAGFLCFGGAVLSSPNDNETGML 833

  Fly   104 CMSYVKCIRGDLVRQRCPAGSNFNVISKNCQMSRTGSC--ASPKEICLEGELQVDSEDC-AGYL- 164
            |.|...|..|......||.|:    .|.:.|:|:...|  .:|...|.|..|...|..| .||.
Zfish   834 CPSGFYCPAGSFAGIPCPKGT----FSNSSQLSKISQCQNCTPGFYCSEPGLTAVSGPCLPGYYC 894

  Fly   165 ----------------------ECLNGGLVKEKCPIGSYFEPIFKLCQLDENGVCSSSSSECTDG 207
                                  .|:.|..|...||:|:.        :.|..|..:.....|..|
Zfish   895 SEGSPSAAPVSAVYGSVCPPGHYCVVGSAVPAPCPVGTR--------RPDSRGKATDDCMPCPGG 951

  Fly   208 EVRVDPNNCAGYFNCENGRLITKTCPSGTYFEPTYKTCTVDLKGVCVEPPAKCTEGQLKIDPNNC 272
            :           |..:.|:...|.||:|      :....:......|..|..|.||  ...||..
Zfish   952 Q-----------FQDQRGQSECKPCPTG------FHCINLTSGSTGVSSPIICPEG--FYCPNET 997

  Fly   273 AGYLKCIDGEFVEEKCPGGTYYD----FKLETCLV-------------DTEGVCVTIRKLCIEGL 320
            .      .|..|  .||.|||.|    ...|.|||             :..|.|.. ..||....
Zfish   998 Q------SGNPV--PCPKGTYSDSLGLISAEQCLVCPMGYFCGSVGLSNPSGACAP-GFLCFVQA 1053

  Fly   321 REKDPKDCAAYTQCIRGRVESVMCDSGRYFNVTQGECLADLYEVCLKSRKEHFRIVEHHQYDEST 385
            ...:|.|.:..:.|..|    ..|..|    ...|||....|.....|..|           :|.
Zfish  1054 TVPNPTDNSTGSLCPPG----AFCLLG----TRAGECSEGYYCDWGSSSPE-----------QSL 1099

  Fly   386 TPNSYQQTESTDADFQSTDSALQEVTSQNSCIFDLNGACVGQSTICTEGKKQRDINNC------- 443
            .|..:.....|:...                      ||.|.:.....|...|:  ||
Zfish  1100 CPAGFYCPAGTNKPL----------------------ACTGGTFSSVMGNSHRE--NCEPCPLGF 1140

  Fly   444 -------AGYLKCIDGEF--------VEEECPESTYY----DSNLETCLVDNYGACVTS------ 483
                   |..|.|..|.|        .:..||..|..    .:::|.||....|....|
Zfish  1141 YCQGDAVAEPLPCPPGHFCPLSTSQGTQFPCPPGTMQPQSGTASVEECLPCPSGMFCASHGLSEP 1205

  Fly   484 TSICVEGI---------------VEEDPKD-CAGYNQCVRGKVEPLKCAFGRYFN--GTQG--EC 528
            |..|.:|.               :|....: |...:.|..|...||.|..|.:.:  |..|  :|
Zfish  1206 TGRCQDGFHCPSGATSPDGTGNTIESTGNNICPPGHYCPTGIGSPLPCPAGTFSSSPGLSGPEQC 1270

  Fly   529 LIDLDEVCAKSSQVDYDRDLEQFQYSQSTSEYLLEYTNTDTTIADFSTESSNADFNRYTDSNSYT 593
                 :.|...                    |..|.|   ..:........:|.:
Zfish  1271 -----QPCPPG--------------------YFCEQT---AMVHPSQAALCDAGY---------- 1297

  Fly   594 DTESTTNDVPTSTEVSTFDLKTTDLSLQFTTLDGVDNLDINTGTCVYNNTLFIEGIREVNPQD-C 657
                                                       .|       |.|.|...|.| .
Zfish  1298 -------------------------------------------VC-------INGSRSARPVDGL 1312

  Fly   658 AGYI-----ECFGGVAKELKCDSGRYFNETQRNCSVDVDEICLKSDKTIVLDLQTTTESTPNFTT 717
            .|||     .|..|...|:.|:.|.|       .||.....||......:.....|.|.:|
Zfish  1313 QGYICPSGHSCPIGAPLEVPCEPGTY-------SSVPGAARCLLCPAGTMCPSPGTLEPSP---- 1366

  Fly   718 SVDPFAKCRDGQLRLDPKNCAGFLKCVDGELKEEM----------CPSGFFYNSTSSKCMVDIRA 772
                   |..|  ...|...|..:.|..|.|.:..          ||:|.:.:|..:.   ..:.
Zfish  1367 -------CPMG--HFCPVGTAEAVPCPVGTLGQGTRAQSEAACVPCPTGLYCSSAGTS---QPQG 1419

  Fly   773 TCVTNIKYCIEGVREEDPNNCAGYRQ-------------------CIRGLVQNLN---------- 808
            .|.... :|..|.....|.|..||.:                   |..|.::||.
Zfish  1420 QCQQGY-FCQGGSPNPAPLNTTGYLRNGPCPQGHFCPSGTLMPLPCPAGSIRNLTGGYSLESCLP 1483

  Fly   809 CPLGQYFNVAERD-----------CLMDVHKVCARTEEVYKSDEVQHNDTGPPMTKP-------- 854
            ||.|.|......|           |.:|   ..:.|...:...:......|.|:..|
Zfish  1484 CPAGHYCASEGLDAPTGPCAAGFYCPVD---FSSTTAHAFLCPKGHFCPLGSPLALPCPTGQYQP 1545

  Fly   855 ---DESCIRDINGVCVDPLAKCREG---QHKL--DPNNCAGYLKCQNGELIEELCPNGFYYDFLM 911
               .::||            .||.|   :..:  ||..|..:..|....::.:.||||.|....:
Zfish  1546 NPGSDNCI------------PCRPGFYCEEAIIGDPRPCPPHSYCPAATMVPQPCPNGTYTPSEV 1598

  Fly   912 ---------------KICLVDR-RGICVTNIQICDEGALEEDPHD------------------C- 941
                           |.|...: :|:|.... :|..|:.:..|..                  |
Zfish  1599 GGLQEERECLPCPSGKFCKAGQVKGLCAAGF-LCISGSSDFTPQSSFLINRDQCEWGAQCAGPCP 1662

  Fly   942 AGYRQCIDGQVENLKCPFGTYFNVP----LRDCL 971
            ||| .|.:|..|.|.||..|....|    |||||
Zfish  1663 AGY-YCPEGTEEPLSCPSNTLRENPGASSLRDCL 1695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31077	NP_733185.2	CBM_14	43..81	CDD:279884	12/41 (29%)
		ChtBD2	<212..245	CDD:214696	6/32 (19%)
		CBM_14	267..308	CDD:279884	14/57 (25%)
		CBM_14	439..472	CDD:279884	11/58 (19%)
		CBM_14	733..769	CDD:279884	9/45 (20%)
		CBM_14	881..914	CDD:279884	10/47 (21%)
si:ch211-286b4.4	XP_021322239.1	Ephrin_rec_like	<945..983	CDD:311571	9/54 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010