DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31076 and MSC7

DIOPT Version :9

Sequence 1:	NP_733184.2	Gene:	CG31076 / 318582	FlyBaseID:	FBgn0051076	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_011904.1	Gene:	MSC7 / 856434	SGDID:	S000001081	Length:	644	Species:	Saccharomyces cerevisiae

Alignment Length:	160	Identity:	34/160 - (21%)
Similarity:	59/160 - (36%)	Gaps:	36/160 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ENNDSQLILVQQNLRTLPQELVKKHADHVEQLDLSHNCLKDLSWLAD--FEQLRHLVLDS----N 63
            ||.|..:.::...:...|.. .....||:|.:|:.       :.::|  |::|..||.|:    .
Yeast   400 ENYDDLVKILNDRMTANPLR-QGSDIDHLENVDMG-------AMISDNRFDELEALVKDAVAKGA 456

  Fly    64 RMHEAHLRTLTCPLPQ---LEVLMLNKNEFSDLPTTMRLIRK--FFPNLQYLSLHGNPIC----- 118
            |:.:...|......||   .:..:|     .|:...|::.:.  |.|.|..:.......|
Yeast   457 RLLQGGSRFKHPKYPQGHYFQPTLL-----VDVTPEMKIAQNEVFGPILVMMKAKNTDHCVQLAN 516

  Fly   119 --PDGLELQPFSTYLRYDYEYYSNYIAQSL 146
              |.||....|...::     ..||:|.||
Yeast   517 SAPFGLGGSVFGADIK-----ECNYVANSL 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31076	NP_733184.2	LRR_8	11..65	CDD:290566	11/59 (19%)
		leucine-rich repeat	11..32	CDD:275378	1/20 (5%)
		leucine-rich repeat	33..54	CDD:275378	4/22 (18%)
		leucine-rich repeat	55..79	CDD:275378	6/27 (22%)
		leucine-rich repeat	80..106	CDD:275378	4/27 (15%)
MSC7	NP_011904.1	ALDH_F15-22	115..590	CDD:143416	34/160 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900