DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31076 and MESK4

DIOPT Version :9

Sequence 1:	NP_733184.2	Gene:	CG31076 / 318582	FlyBaseID:	FBgn0051076	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_001262650.1	Gene:	MESK4 / 64872	FlyBaseID:	FBgn0043069	Length:	280	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	48/148 - (32%)
Similarity:	76/148 - (51%)	Gaps:	16/148 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NDSQLILVQQNLRTLPQELVKKHADHVEQLDLSHNCLKDLSWLADFEQLRHLVLDSNRMHEAHLR 71
            ::.::.|..:||:|:|:.|..|.|...:.||||||..::|.:|:.||.|..|:||.|    .:|.
  Fly    85 DNGRISLAYENLKTIPRRLADKFAAQTKFLDLSHNDFRNLRFLSFFEDLDTLILDRN----VNLD 145

  Fly    72 TLTCP-LPQLEVLMLNKNEFSDLPTTMRLIRKFFPNLQYLSLHGNPICPDGLELQPFSTYLRYDY 135
            ..|.| ||.|.:|.:|..:.:::...:..|.:..|.|..||..|||    |:...       :..
  Fly   146 INTFPYLPSLRILWINNCDIANITDWIHRIERHCPALDQLSCMGNP----GIRTV-------FGG 199

  Fly   136 EYYSNYIAQSLSKLKFLD 153
            :....||.|.|.:||:||
  Fly   200 QGPREYILQVLPQLKYLD 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31076	NP_733184.2	LRR_8	11..65	CDD:290566	23/53 (43%)
		leucine-rich repeat	11..32	CDD:275378	8/20 (40%)
		leucine-rich repeat	33..54	CDD:275378	9/20 (45%)
		leucine-rich repeat	55..79	CDD:275378	9/24 (38%)
		leucine-rich repeat	80..106	CDD:275378	4/25 (16%)
MESK4	NP_001262650.1	leucine-rich repeat	111..132	CDD:275378	9/20 (45%)
		leucine-rich repeat	133..154	CDD:275378	9/24 (38%)
		leucine-rich repeat	155..181	CDD:275378	4/25 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D438561at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41579
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850