DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(r) and CG9674

DIOPT Version :9

Sequence 1:	NP_727320.1	Gene:	su(r) / 31858	FlyBaseID:	FBgn0086450	Length:	1031	Species:	Drosophila melanogaster
Sequence 2:	NP_001246804.1	Gene:	CG9674 / 39878	FlyBaseID:	FBgn0036663	Length:	2115	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	129/523 - (24%)
Similarity:	210/523 - (40%)	Gaps:	77/523 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VKTQCSVVPTKQTKENKKHWKRNADHAAPPCTTLANDFSDIKHTTLSERGALEEAARCLKCADAP 88
            ||.:....|.:...|.:|.|               ::..:..|.   .:....:||||::|....
  Fly  1628 VKYKRESAPYRDAGERQKDW---------------DEVYNFPHV---RKNLKVQAARCMECGVPF 1674

  Fly    89 CQKS---CPTQLDIKSFITSIANKNFYGAAKAIFSDNPLGLTCGMVCPTSDLCVGGCNLQASEAG 150
            ||.:   ||....|..:...:.:..:..|.:.:...|......|.|||..  |.|.|.|..||..
  Fly  1675 CQSNSTGCPLGNIIPKWNDLVFHGEWQEALRQLLQTNNFPEFTGRVCPAP--CEGSCVLGISEPA 1737

  Fly   151 PINIGGLQQFATEVFKKMGVRQRRTPQAEANPLSQKIALVGGGPASLSCATFLARLGYRDVTIYE 215
             :.|..::....:...:.|..:...|:...   .:::|:||.||:.|:.:..|.|.|: .||::|
  Fly  1738 -VTIKNIECAIIDHAFEQGWIKPEIPEVRT---GKRVAIVGSGPSGLAASQQLNRAGH-FVTVFE 1797

  Fly   216 RRSYLGGLSAAEIPQYRLPIDAVNFEIDLVRDLGVRIETGRSLGTKDLTIQGLLSTGHDAVFVGI 280
            |...:|||....||..:|..:.|...:||:.|.|:...|...:| |||..:.||.. :|||.:..
  Fly  1798 RNDRVGGLLQYGIPTMKLSKEVVKRRVDLMADEGIEFRTNVHVG-KDLKAEQLLQE-YDAVLLTT 1860

  Fly   281 GLPEPKLNPIFAGLQPSNGFYTSKNFLPLVSDGSKPGLCACKAAAGLPKLHGNVIVLGAGDTAFD 345
            |...|:..|:  ..:...|.:.:..||.........|.....:|||     .|||::|.|||..|
  Fly  1861 GSTWPRDLPL--ANRDLKGIHFAMEFLEAQQKKQLGGKNDIISAAG-----KNVIIIGGGDTGCD 1918

  Fly   346 CATSALRCGARRVFV----------------------VFRKGSSGIRAVPEEVEL--ARDERCEL 386
            |..::||.||:.:..                      |||     :....|||:|  .:|.|
  Fly  1919 CIATSLRQGAKSITTFEILPEPPQKRAQDNPWPQWPKVFR-----VDYGHEEVKLKWGKDPR--- 1975

  Fly   387 LPYLSPRKVIV-KDGLITAMEFCRTE--QNENDEWVEDE--EQTQRLKANFVISAFGSGLEDQDV 446
             .|.:..|..| ::|.|..:.....|  :.|..:|...|  ...:...|:.::.|.|....::.|
  Fly  1976 -QYCTTTKEFVGENGAIKGVNTVEVEWTKTETGQWRMQEVAGSEKYFPADLILLAMGFLGPEKTV 2039

  Fly   447 KAALA-PLQFRGELPVVDRVTMQSSVKQVFLGGDLAGVANTTVESVNDGKVAAWSIHCQLQGLPL 510
            .:.|. .|..||.:...:.....|:.| ||..||.....:..|.::.:|:.||..:...|.|.|.
  Fly  2040 PSELGLELDPRGNIKASNGQYGTSNSK-VFAAGDCRRGQSLVVWAITEGRQAARQVDSYLTGRPS 2103

  Fly   511 DTP 513
            ..|
  Fly  2104 GLP 2106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(r)	NP_727320.1	PRK11749	55..507	CDD:236967	120/484 (25%)
		Fer4_20	58..170	CDD:291363	24/114 (21%)
		NAD_binding_8	190..>234	CDD:290186	17/43 (40%)
		PRK08318	527..1008	CDD:236237
		DHPD_FMN	527..829	CDD:239244
		Fer4_9	953..997	CDD:289930
CG9674	NP_001246804.1	gltB	75..1565	CDD:236968
		GATase_2	88..504	CDD:278726
		Glu_syn_central	543..828	CDD:282720
		GltS_FMN	918..1271	CDD:239202
		gltB_C	1316..1565	CDD:238482
		gltD	1623..2106	CDD:237213	128/521 (25%)
		Fer4_8	1645..1756	CDD:302761	26/131 (20%)
		NAD_binding_8	1772..>1804	CDD:290186	12/32 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840