Protein Alignment spn-D and RAD51

DIOPT Version :9

• Sequence 1: NP_733200.1
• Gene: spn-D / 318579
• FlyBaseID: FBgn0003482
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001157741.1
• Gene: RAD51 / 5888
• HGNCID: 9817
• Length: 340
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 72/297 - (24%)
• Similarity: 119/297 - (40%)
• Gaps: 62/297 - (20%)

  Fly    15 EAIERRPSVSHENFRIFDKSCWDISQSASNKILTGKKAL---------------------DTHFG 58
            ||:...|.....|.:       .||::.::||||..:::                     |:...
Human    50 EAVAYAPKKELINIK-------GISEAKADKILTESRSVARLECNSVILVYCTLRLSGSSDSPAS 107

  Fly    59 --------GGISLGHLVELIGNSGTGKTQMCLQLCLNVQIPKAAGGLEGSALFIDTRQDFHPDRL 115
                    |||..|.:.|:.|...|||||:|..|.:..|:|...||.||.|::|||...|.|:||
Human   108 ASRVVGTTGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERL 172

  Fly   116 MGLALKLERQYAHRVPEFKAHKMLQKIHYVRCPKLDQLMATVLSCHRHLVDHPDIKLIVIDSLAF 180
            :.:|    .:|.     .....:|..:.|.|....|.....:......:|: ....|:::||...
Human   173 LAVA----ERYG-----LSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVE-SRYALLIVDSATA 227

  Fly   181 TLRMLEDGAHRYEM---LLELHESMRRLQRQHELTWVFTNVLTHRYVKQ-----KFQVEPAL--- 234
            ..|  .|.:.|.|:   .:.|...:|.|.|..:...|.. |:|::.|.|     .|..:|..
Human   228 LYR--TDYSGRGELSARQMHLARFLRMLLRLADEFGVAV-VITNQVVAQVDGAAMFAADPKKPIG 289

  Fly   235 GDLHSHLINERIWF-SGSSELHLGKSWRTSRLIKESE 270
            |::.:|....|::. .|..|..:.|.: .|..:.|:|
Human   290 GNIIAHASTTRLYLRKGRGETRICKIY-DSPCLPEAE 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-D	NP_733200.1	P-loop_NTPase	46..249	CDD:304359	59/243 (24%)
RAD51	NP_001157741.1	recomb_RAD51	25..340	CDD:274048	72/297 (24%)
		HHH_5	32..77	CDD:291205	9/33 (27%)
		Rad51_DMC1_radA	116..336	CDD:238543	61/224 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22942
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910