DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-D and Rad51c

DIOPT Version :9

Sequence 1:	NP_733200.1	Gene:	spn-D / 318579	FlyBaseID:	FBgn0003482	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_038942551.1	Gene:	Rad51c / 497976	RGDID:	1563765	Length:	402	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	89/282 - (31%)
Similarity:	136/282 - (48%)	Gaps:	32/282 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SQPEAIE-----RRPSVSHE----NFRIFDKSCWDI----SQSASNKILTGKKALDTHFGGGISL 63
            |:.||:|     ||..::::    ...:.:|.|..:    .:.....|:|...|||...||||.|
  Rat    80 SKEEALETLQILRRECLTNKPRCAGTSVANKKCTALELLEQEHTQGFIITFCSALDNILGGGIPL 144

  Fly    64 GHLVELIGNSGTGKTQMCLQLCLNVQIPKAAGGLEGSALFIDTRQDFHPDRLMGLA------LKL 122
            ....|:.|..|.||||:|:||.::||||:..||:.|.|:||||...|..||::.||      |.|
  Rat   145 MKTTEVCGVPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVSLATACIQHLHL 209

  Fly   123 ------ERQYAHRVPEFKAHKMLQKIHYVRCPKLDQLMATVLSCHRHLVDHPDIKLIVIDSLAFT 181
                  |.:....:.:|....:|..|:|.||....:|:|.|......|.||..::|::||.:||.
  Rat   210 IAGTHTEEEQQKALKDFTLENILSHIYYFRCHDYTELLAQVYLLPDFLSDHSKVQLVIIDGIAFP 274

  Fly   182 LRM-LEDGAHRYEMLLELHESMRRLQRQHELTWVFTNVLTHRYVKQKFQVEPALGDLHSHLINER 245
            .|. |:|...|..:|..|.:.:..|..:|.|..:.||.:|.:..|.:..:.||||:...|....|
  Rat   275 FRHDLDDLFLRTRLLNGLAQQLISLANKHRLAVILTNQMTTKIDKNQASLVPALGESWGHAATIR 339

  Fly   246 IWFSGSSELHLGKSWRTSRLIK 267
            :.|      |..:..|.:.|.|
  Rat   340 LIF------HWEQKQRFATLYK 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-D	NP_733200.1	P-loop_NTPase	46..249	CDD:304359	76/215 (35%)
Rad51c	XP_038942551.1	Sms	97..>166	CDD:223993	21/68 (31%)
Rad51c	XP_038942551.1	Rad51C	145..357	CDD:410900	71/217 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351003
Domainoid	1	1.000	122	1.000	Domainoid score	I5541
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4659
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1345899at2759
OrthoFinder	1	1.000	-	-		FOG0006918
OrthoInspector	1	1.000	-	-		oto95586
orthoMCL	1	0.900	-	-		OOG6_104543
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4389
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.660