DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-D and rad51c

DIOPT Version :9

Sequence 1:	NP_733200.1	Gene:	spn-D / 318579	FlyBaseID:	FBgn0003482	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001006101.1	Gene:	rad51c / 450081	ZFINID:	ZDB-GENE-041010-204	Length:	362	Species:	Danio rerio

Alignment Length:	227	Identity:	75/227 - (33%)
Similarity:	116/227 - (51%)	Gaps:	10/227 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ILTGKKALDTHFGGGISLGHLVELIGNSGTGKTQMCLQLCLNVQIPKAAGGLEGSALFIDTRQDF 110
            |:|....||...|||:.:|...|:.|..|.||||:|:||.::||||...|||.|.||:|||...|
Zfish    86 IVTFCSGLDDAIGGGVPVGKTTEICGAPGVGKTQLCMQLAVDVQIPVFFGGLGGKALYIDTEGSF 150

  Fly   111 HPDRLMGLA---------LKLERQYAHRVPEFKAHKMLQKIHYVRCPKLDQLMATVLSCHRHLVD 166
            ...|:..:|         |..:.:....:.|....|:|..:..|||....:|:|.|......|.:
Zfish   151 LVQRVADMAEAAVQHCTLLAEDTEQKGALEELNVEKILSNLFLVRCHDYVKLLAEVYLLPDFLSE 215

  Fly   167 HPDIKLIVIDSLAFTLRM-LEDGAHRYEMLLELHESMRRLQRQHELTWVFTNVLTHRYVKQKFQV 230
            ||:::|:||||:||..|. .||.:.|..:|..|.:.:.:|..||.:..|.||.:|.|....:.::
Zfish   216 HPEVRLVVIDSIAFPFRHDFEDLSQRTRLLNGLAQQLIQLATQHRVAVVLTNQMTTRVSNGQSKL 280

  Fly   231 EPALGDLHSHLINERIWFSGSSELHLGKSWRT 262
            .||||:...|...:|:......:..|...:::
Zfish   281 VPALGESWGHAATQRLILHWEGQRRLASLYKS 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-D	NP_733200.1	P-loop_NTPase	46..249	CDD:304359	74/212 (35%)
rad51c	NP_001006101.1	radA	3..331	CDD:235273	75/227 (33%)
rad51c	NP_001006101.1	Rad51_DMC1_radA	86..330	CDD:238543	75/227 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592720
Domainoid	1	1.000	124	1.000	Domainoid score	I5479
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I4696
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1345899at2759
OrthoFinder	1	1.000	-	-		FOG0006918
OrthoInspector	1	1.000	-	-		oto39814
orthoMCL	1	0.900	-	-		OOG6_104543
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1065
SonicParanoid	1	1.000	-	-		X4389
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.830