DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-D and rad51

DIOPT Version :9

Sequence 1:	NP_733200.1	Gene:	spn-D / 318579	FlyBaseID:	FBgn0003482	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_998371.2	Gene:	rad51 / 406487	ZFINID:	ZDB-GENE-040426-2286	Length:	340	Species:	Danio rerio

Alignment Length:	244	Identity:	69/244 - (28%)
Similarity:	109/244 - (44%)	Gaps:	38/244 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KILTGKKALDTHFGGGISLGHLVELIGNSGTGKTQMCLQLCLNVQIPKAAGGLEGSALFIDTRQD 109
            :|.||.|.||....|||..|.:.|:.|...|||||:|..|.:..|:|...||.||.|::|||...
Zfish   102 QISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGT 166

  Fly   110 FHPDRLMGLALKLERQYAHRVPEFKAHKMLQKIHYVRCPKLD---QLM---ATVLSCHRHLVDHP 168
            |.|:||:.:|    .:|.     .....:|..:.|.|....|   ||:   :.:::..|:
Zfish   167 FRPERLLAVA----ERYG-----LVGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRY----- 217

  Fly   169 DIKLIVIDSLAFTLRMLEDGAHRYEMLL---ELHESMRRLQRQHELTWVFTNVLTHRYVKQ---- 226
              .|:::||.....|  .|.:.|.|:..   .|...:|.|.|..:...|.. |:|::.|.|
Zfish   218 --ALLIVDSATALYR--TDYSGRGELSARQGHLGRFLRMLLRLADEFGVAV-VITNQVVAQVDGA 277

  Fly   227 -KFQVEPAL---GDLHSHLINERIWF-SGSSELHLGKSWRTSRLIKESE 270
             .|..:|..   |::.:|....|::. .|..|..:.|.: .|..:.|:|
Zfish   278 AMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIY-DSPCLPEAE 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-D	NP_733200.1	P-loop_NTPase	46..249	CDD:304359	63/220 (29%)
rad51	NP_998371.2	recomb_RAD51	26..340	CDD:274048	69/244 (28%)
		HHH_5	32..81	CDD:291205
		Rad51_DMC1_radA	103..336	CDD:238543	69/243 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22942
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910