Protein Alignment ppk31 and ASIC3

DIOPT Version :9

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_064717.1
• Gene: ASIC3 / 9311
• HGNCID: 101
• Length: 549
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 81/446 - (18%)
• Similarity: 143/446 - (32%)
• Gaps: 155/446 - (34%)

  Fly    48 FPAITVCEIYNAERI--------WDLSDSNFGVEHDMHVDDFISEIVFYRGVCSSCEDCSRMRCP 104
            |||:|:|.|....|.        | ...:..|::...|.       .|.|.:       .|...|
Human    86 FPAVTLCNINPLRRSRLTPNDLHW-AGSALLGLDPAEHA-------AFLRAL-------GRPPAP 135

  Fly   105 SNFT-----HLVDVFRTKCHQL---LVNCTYLNKLFDC-CDQFLPLPTEYGLCFSFNSHQARKVS 160
            ..|.     .:..::....|.|   |::|.:..:  .| .:.|..:.|..|.|::|||  ....:
Human   136 PGFMPSPTFDMAQLYARAGHSLDDMLLDCRFRGQ--PCGPENFTTIFTRMGKCYTFNS--GADGA 196

  Fly   161 HLQFTNNRMTGPGHLSFHAAADIQLYVHAPI-----DVPYQFSEGMIRETVLLGHYKELILNVIE 220
            .|..|.....|.|   .....|:|...:.|:     :.|::..   ||               ::
Human   197 ELLTTTRGGMGNG---LDIMLDVQQEEYLPVWRDNEETPFEVG---IR---------------VQ 240

  Fly   221 VHNDES--VQD-------------LSMEQRRCRY-------------GHEHVPERQGIYDF---- 253
            :|:.|.  :.|             :|.:|::..:             ...:.||.......
Human   241 IHSQEEPPIIDQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPS 305

  Fly   254 ----YSYSGCVVECTVLLQLDNCNCTSHFMAIPGQNYLPVCDVRGLICLTRIRDKIMTERKSCEC 314
                |:..||.:.|........|.|...:|  ||.  :|||..:............|..:.||.|
Human   306 PSPPYTLMGCRLACETRYVARKCGCRMVYM--PGD--VPVCSPQQYKNCAHPAIDAMLRKDSCAC 366

  Fly   315 MSSCEEPEYNIIYNSADEDDEASDEVSEIRVALVELPTQ---RYVRR--------VTKTIL---- 364
            .:.|....|             :.|:|.:|:     |::   |::.|        :.:.:|
Human   367 PNPCASTRY-------------AKELSMVRI-----PSRAAARFLARKLNRSEAYIAENVLALDI 413

  Fly   365 -------------------DFLISLGGLVGLFFNTSALRIVETI-VICLRYRKTIV 400
                               :.|..:||.:|||...|.|.|:|.: .:|..:|..::
Human   414 FFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASLLTILEILDYLCEVFRDKVL 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	59/335 (18%)
ASIC3	NP_064717.1	ASC	20..534	CDD:295594	81/446 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..307		2/21 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920