Protein Alignment ppk31 and scnn1b

DIOPT Version :10

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 101/554 - (18%)
• Similarity: 174/554 - (31%)
• Gaps: 223/554 - (40%)

  Fly    24 LLNSYLSSSVSFNLDTIYLNWNSTFPAITVCEI--YNAERIWDL--------------------- 65
            |:.:|||..||.:|...:....  |||:|||..  |...|:..|
 Frog    76 LILTYLSYGVSVSLSIGFKTME--FPAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQFSSQD 138

  Fly    66 -------SDSNFGVEHDMHVDDFISEIVF------------------------------------ 87
                   |.:|..|..|..:.:.|..:|.
 Frog   139 QANTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQTSY 203

  Fly    88 ---YRGVCSSCEDCSRMRCPSNFT------------HLVDVFRT-----------KCHQLLVN-- 124
               |:.....|.:.:......|||            .|..:|..           |...|::.
 Frog   204 SQRYKVAMKLCTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLILTCL 268

  Fly   125 -----CTYLN--KLFDCCDQFLPLPTEYGLCFSFN-------------------------SHQAR 157
                 |:|.|  :::|         .:||.|:.||                         ..|..
 Frog   269 FGGQPCSYRNFTRIYD---------ADYGNCYIFNWGQEGEDPMASANPGADFGLKLVLDIEQGE 324

  Fly   158 KVSHLQFTNNRMTGPGHLSFHAAADIQLYVHAPIDVPYQFSEGMIRETVLLGHY----KELILNV 218
            .:.::|.|             |||  :|.:|.....|:      :::   ||.|    .|..:.|
 Frog   325 YLPYVQTT-------------AAA--RLILHQQRSFPF------VKD---LGIYAMPGTETSIAV 365

  Fly   219 IEVHNDESVQDLSMEQRRCRYGHEHVPERQGIYDF---YSYSGCVVECTVLLQLDNCNCTSHFMA 280
            :.    :.::.:......|......:|.:....:|   ||...|:..|.....:..|.|..:...
 Frog   366 LV----DQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGCADYQYP 426

  Fly   281 IP-GQNY---------LPVCDVRGLICLTRIRDKIMTERKSC--ECMSSCEEPEYNIIYNSAD-- 331
            :| |..|         :|        |...:||.: .:|:||  .|...|.:.:|.::.:.||
 Frog   427 LPNGSEYCSNDKYPDWVP--------CYYGLRDSV-ADRESCISLCQQPCNDTQYKMVISMADWP 482

  Fly   332 -------------EDDEASDEVSEIRVALVELPT--QRY-VRRVTKT----ILDFLISLGGLVGL 376
                         .:.::|..::..|..:|.|..  |.: .|.:|::    ::..|.:|||..|.
 Frog   483 SAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRSITESEATNVVWLLSNLGGQFGF 547

  Fly   377 FFNTSALRIV---ETIVICLRYRKTIVK---WVK 404
            :...|.|.|:   |.|:.|:..  ||:|   |:|
 Frog   548 WMGGSVLCIIEFGEIIIDCVWI--TILKLLAWIK 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	36..387	CDD:459966	87/520 (17%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	101/554 (18%)