Protein Alignment ppk31 and ASIC5

DIOPT Version :9

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_059115.1
• Gene: ASIC5 / 51802
• HGNCID: 17537
• Length: 505
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 114/467 - (24%)
• Similarity: 189/467 - (40%)
• Gaps: 112/467 - (23%)

  Fly     4 ILYLVTFYHTLPFFA-NVSLSLLNSYLSSSVSFNLDTIYLNWNSTFPAITVCEIYNAERIWDLSD 67
            :|:||....::.... .:.:.||| |.:...:.:::..|:. ...|||:|.|   |..|....:.
Human    63 VLWLVVVLGSVSLVTWQIYIRLLN-YFTWPTTTSIEVQYVE-KMEFPAVTFC---NLNRFQTDAV 122

  Fly    68 SNFGVEHDM-HVDDFISEIVFYRGVCS----SCEDCSRMRCPSNFTHLVDVFRTKCHQL----LV 123
            :.|||...: |:   :|:::..:.:.:    |.|.........||: :|:..|.|...|    |:
Human   123 AKFGVIFFLWHI---VSKVLHLQEITANSTGSREATDFAASHQNFS-IVEFIRNKGFYLNNSTLL 183

  Fly   124 NCTYLNKLFDCCDQ-FLPLPTEYGLCFSFNSHQA----RKVS-------------HLQFTNNRMT 170
            :|.:..|  .|..: |..:.||||.||:||..:.    ||||             ...||:|...
Human   184 DCEFFGK--PCSPKDFAHVFTEYGNCFTFNHGETLQAKRKVSVSGRGLSLLFNVNQEAFTDNPAL 246

  Fly   171 GPGHLSFHAAADIQLYVHAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHNDESVQDLSMEQR 235
            |      ...|.|...:|:|..|| || :|       ||     :|:.:.:|...:::.:....:
Human   247 G------FVDAGIIFVIHSPKKVP-QF-DG-------LG-----LLSPVGMHARVTIRQVKTVHQ 291

  Fly   236 RCRYGHEHVPERQGIYDFYSYSGCVVECTVLLQLDNCNCTSHFMAIPGQNYLPVCDVRGLI-CLT 299
            ...:|..:...:...:..||.|||:.||........|.|..  ..:||  |...||::... |::
Human   292 EYPWGECNPNIKLQNFSSYSTSGCLKECKAQHIKKQCGCVP--FLLPG--YGIECDLQKYFSCVS 352

  Fly   300 RIRDKIM--------TERKSCECMSSCEEPEY--NIIYNSADEDDE---ASDEVSEIRVALVELP 351
            .:.|.|.        |...||..  ||||.||  .|.|:|......   .|.::::.|
Human   353 PVLDHIEFKDLCTVGTHNSSCPV--SCEEIEYPATISYSSFPSQKALKYLSKKLNQSR------- 408

  Fly   352 TQRYVR---------------RVTK-----TILDFLISLGGLVGLFFNTSALRIVETIVICLRYR 396
              :|:|               ::|:     ::.:.|..|||.:|||...|.:.|:|.|    .|.
Human   409 --KYIRENLVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEII----EYL 467

  Fly   397 KTIVKWVKRFFL 408
            .|...|:..|||
Human   468 FTNFYWICIFFL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	76/311 (24%)
ASIC5	NP_059115.1	ASC	41..466	CDD:279230	108/452 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820