Protein Alignment ppk31 and ASIC1

DIOPT Version :9

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_064423.2
• Gene: ASIC1 / 41
• HGNCID: 100
• Length: 574
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 78/393 - (19%)
• Similarity: 138/393 - (35%)
• Gaps: 119/393 - (30%)

  Fly    47 TFPAITVC-------------EIYNAERIWDLSDSNFGVEHDMHVDDFISEIVFYRGVCSSCEDC 98
            ||||:|:|             ::|:|..:..|.::.:.:......|:...||:         :|.
Human    86 TFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEIL---------QDK 141

  Fly    99 SRMRC----PSNFTHLVDVFRTKCHQLLVNCTYLNKLFDC-CDQFLPLPTEYGLCFSFNSHQARK 158
            :..|.    |.|.....|........:|::|.:..::  | .:.|..:.|.||.|::|||.:..:
Human   142 ANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEV--CSAEDFKVVFTRYGKCYTFNSGRDGR 204

  Fly   159 VSHLQFTNNRMTGPGHLSFHAAADIQLYVHAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHN 223
             ..|: |....||.|   .....|||...:.|:       .|...||......|      :::|:
Human   205 -PRLK-TMKGGTGNG---LEIMLDIQQDEYLPV-------WGETDETSFEAGIK------VQIHS 251

  Fly   224 DES---VQDLS-------------MEQRRCRYGHEHVPERQG------------IYDFYSYSGCV 260
            .:.   :..|.             .|||..     ::|...|            .:|.||.:.|.
Human   252 QDEPPFIDQLGFGVAPGFQTFVACQEQRLI-----YLPPPWGTCKAVTMDSDLDFFDSYSITACR 311

  Fly   261 VECTVLLQLDNCNCTSHFMAIPGQNYLPVCDVRGL-ICLTRIRDKIM-TERKSCECMSSCEEPEY 323
            ::|.....::||||  ..:.:||.  .|.|..... .|.....|.:: .:::.|.|...|....|
Human   312 IDCETRYLVENCNC--RMVHMPGD--APYCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRY 372

  Fly   324 NIIYNSADEDDEASDEVSEIRVALVELPTQRYVRRVTKTILDFLISLGGLVGLFFNTSALRIVET 388
                         ..|:|     :|::|::...:.:.|.               ||.|...|.|.
Human   373 -------------GKELS-----MVKIPSKASAKYLAKK---------------FNKSEQYIGEN 404

  Fly   389 IVI 391
            |::
Human   405 ILV 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	57/290 (20%)
ASIC1	NP_064423.2	ENaC	19..556	CDD:273304	78/393 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920