DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk31 and asic1c

DIOPT Version :9

Sequence 1:	NP_001097944.1	Gene:	ppk31 / 318575	FlyBaseID:	FBgn0051065	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_021325802.1	Gene:	asic1c / 407670	ZFINID:	ZDB-GENE-040513-3	Length:	562	Species:	Danio rerio

Alignment Length:	454	Identity:	95/454 - (20%)
Similarity:	156/454 - (34%)	Gaps:	135/454 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 VSLSLLNSYLSSSVSFNLD-----TIYLNW--NSTFPAITVC-------------EIYNAERIWD 64
            |.|.||.::..:.:.:.|.     .||:.|  |.||||||.|             ::|.:....|
Zfish    72 VCLGLLFTWSWNRILYLLSYPAVTKIYMVWSNNMTFPAITFCNQNRLRVSSLTRDDLYYSGYWMD 136

  Fly    65 LSDSNFG--------VEHDMHVDDFISEIVFYRGVCSSCEDCSRMRCPS----NFTHLVDVFRTK 117
            :...|..        ::|..|.:..:..:           |.|....|.    |.|.::|....:
Zfish   137 ILHLNHTLNRQSVSMLKHSRHRERLLHLL-----------DFSHYSPPPDQSLNTTEMIDRLGHQ 190

  Fly   118 CHQLLV-------NCTYLNKLFDCCDQFLPLPTEYGLCFSFNSHQARKVSHLQFTNNRMTGPG-- 173
            ...:|:       ||||.|        |.|:.|.||.|::|||  ....:.|..|....||.|
Zfish   191 LQDMLLECRFRGENCTYKN--------FTPIYTRYGKCYTFNS--GLDGNPLLTTLKGGTGNGLE 245

  Fly   174 ------------------HLSFHAAADIQLYVHAPIDVPY--QFSEGMIRE-TVLLGHYKELILN 217
                              ..|:.|...:|  :|:..:.|:  |...|:... ...:...::|:|.
Zfish   246 IMLDIQQDEYLPVWGDTDETSYEAGIKVQ--IHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLY 308

  Fly   218 VIEVHNDESVQDLSMEQRRCRYGHEHVPERQGIYDFYSYSGCVVECTVLLQLDNCNCTSHFMAIP 282
            :.....|            ||    ..|.....:..||.:.|.::|.....|:||||  ..:.:|
Zfish   309 LPPPWGD------------CR----SAPMDSEYFSTYSITACRIDCETRYLLENCNC--RMVHMP 355

  Fly   283 GQNYLPVC------DVRGLICLTRIRDKIMTERKS--CECMSSCEEPEYNIIYNSADEDDEAS-- 337
            |.:  .||      |     |.....| .:.|:.:  |.|.:.|....|....:......:||
Zfish   356 GTS--TVCTPEQYKD-----CADPALD-FLVEKDNDYCVCDTPCNMTRYGKELSMVKIPSKASAK 412

  Fly   338 --------------DEVSEIRVALVELPTQRYVRRVTKTILDFLISLGGLVGLFFNTSALRIVE 387
                          |.:..:.:....|..::..::....:...|..:||.:|||...|.|.|:|
Zfish   413 YLAKKFNKTEQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	63/306 (21%)
asic1c	XP_021325802.1	ASC	34..531	CDD:322155	95/454 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020