DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk31 and asic2

DIOPT Version :9

Sequence 1:	NP_001097944.1	Gene:	ppk31 / 318575	FlyBaseID:	FBgn0051065	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_005164179.1	Gene:	asic2 / 407669	ZFINID:	ZDB-GENE-040513-4	Length:	564	Species:	Danio rerio

Alignment Length:	476	Identity:	103/476 - (21%)
Similarity:	164/476 - (34%)	Gaps:	160/476 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LSLLNSYLSSS----VSFNLDT-IYLNW--NSTFPAITVCEIYNAERIWDLSDSN-FGVEH---- 74
            |.||.|:.|:.    ::|...| ::..|  ...||.:|:|. .|..|::.|:.|: :...|
Zfish   100 LGLLLSWSSNRLLHWLAFPTHTRVHTEWAKELAFPTVTICN-NNPVRLYHLTKSDLYFAGHWLGL 163

  Fly    75 ------------DMHVDDFISEIVFYRGVCSSCEDCSRMRCPSNF----THLVDVFRTKCHQLLV 123
                        |:..||       .||..|...|......|..|    ...:|....:...:|:
Zfish   164 LLANRTARPLVLDLLQDD-------RRGWFSKLSDFRLFLPPRRFEGTSLEFMDRLGHQLEDMLL 221

  Fly   124 NCTYLNKLFDC-CDQFLPLPTEYGLCFSFNSHQARKVSHLQFTNNRMTGPGHLSFHAAADIQLYV 187
            .|.|..:  .| ...|..:.|.||.|:.||:.:..|.  |:.|....||.|   .....|||...
Zfish   222 ACKYRGE--PCGAHNFSTVFTRYGKCYMFNAAEEGKT--LRTTMKGGTGNG---LEIMLDIQQDE 279

  Fly   188 HAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHNDES---VQDL------------SMEQRRC 237
            :.|:       .|...||......:      :::|:...   |.:|            :.:::|.
Zfish   280 YLPV-------WGETEETAFEAGVR------VQIHSQAEPPFVHELGFGVAPGFQTFVATQEQRL 331

  Fly   238 RYGHEHVPE----------RQGIYDFYSYSGCVVECTVLLQLDNCNCTSHFMAIPGQNYLPVCDV 292
            .|    :|.          ..|::..||.|.|.:||.....::||||...:|  ||.:  |.|..
Zfish   332 TY----LPPPWGECVSRALDSGLFQVYSVSACRIECETRYIVENCNCRMVYM--PGDS--PYCTP 388

  Fly   293 R--------GLICLTRIRDKIMTERKSCECMSSCEEPEYNIIYNSADEDDEASDEVSEIRVALVE 349
            .        .|..|:.:      |..:|.|.|.|....||             .|:|     :|:
Zfish   389 EQYKDCAEPALAALSAV------EGTNCICRSPCNMTRYN-------------KELS-----MVK 429

  Fly   350 LPTQ---RYVRR--------VTKTIL-----------------------DFLISLGGLVGLFFNT 380
            :|::   ||:.:        :|..||                       ..|..:||.:|||...
Zfish   430 IPSKTSARYLEKKFNRSEKYITDNILVLDVFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGA 494

  Fly   381 SALRIVETIVICLRYRKTIVK 401
            |.|.::|    ...|...:||
Zfish   495 SILTLLE----LFDYAYEVVK 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	70/327 (21%)
asic2	XP_005164179.1	ASC	71..538	CDD:295594	103/476 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020