Protein Alignment ppk31 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 104/546 - (19%)
• Similarity: 167/546 - (30%)
• Gaps: 187/546 - (34%)

  Fly     4 ILYLVTFYHTLPFFANVSLSLLNSYLSSSVSFNLDTIYLNWNS---TFPAITVCEIYNAERIWDL 65
            :|:|.||......||    .|...|||..||.|     :|.||   .|||:|||.: |..|..::
  Rat   115 VLWLCTFGMMYWQFA----LLFEEYLSYPVSLN-----INLNSDKLVFPAVTVCTL-NPYRYTEI 169

  Fly    66 SDSNFGVEHDMHVDDFISEIVF--YRGVCSSCEDCSRMRCPSN-----FTHLVDVFRTK------ 117
            .      |....:|....:.:|  |:...|........|..|.     |.|.:...||.
  Rat   170 K------EELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSG 228

  Fly   118 ----------------------------CHQLLVNCTYL-------------------------- 128
                                        |:|...:|.|.
  Rat   229 RTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSD 293

  Fly   129 -----------NKLFDC------CDQ------FLPLPTEYGLCFSFNSHQARK--VSHLQFTNNR 168
                       |.:|.|      |:|      ..|:   ||.|::||......  :|.:...||.
  Rat   294 TSPALEEEALGNFIFTCRFNQAPCNQANYSKFHHPM---YGNCYTFNDKNNSNLWMSSMPGVNNG 355

  Fly   169 MTGPGHLSFH-----------AAADIQLYVHAPIDVPYQFSEG--MIRETVLLGHYKELILNVIE 220
            ::    |:..           .....::.||.. |.|....:|  .:|..|      |..:::
  Rat   356 LS----LTLRTEQNDFIPLLSTVTGARVMVHGQ-DEPAFMDDGGFNLRPGV------ETSISM-- 407

  Fly   221 VHNDESVQDLSMEQRRCRYGHEHVPERQGIYDFYSYSGCVVECTVLLQLDNCNCTSHFMAIPGQN 285
              ..|::..|......|......||.:......|:...|:..|.....:..|.|.  ::..|...
  Rat   408 --RKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCA--YIFYPKPK 468

  Fly   286 YLPVCDVRGL----ICLTRIRDKIMTERKSCECMSSCEEPEYNIIYN---------SADEDD--- 334
            .:..||.|..    .|..:::.....:  |..|.|.|.:|...|.|.         |....|
  Rat   469 GVEFCDYRKQSSWGYCYYKLQGAFSLD--SLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWIF 531

  Fly   335 ------------EASDEVSEIRVALVELPTQRYVRRVTKTILDFLISLGGLVGLFFNTSALRIVE 387
                        ...:.|:::.:...||..:......:.|::..|.:||....|:|.:|.|.:||
  Rat   532 EMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVE 596

  Fly   388 -------TIVICLRYRKTIVKWVKRF 406
                   .:||      |::..::||
  Rat   597 MAELIFDLLVI------TLLMLLRRF 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	36..387	CDD:459966	85/486 (17%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	104/546 (19%)