DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk31 and flr-1

DIOPT Version :9

Sequence 1:	NP_001097944.1	Gene:	ppk31 / 318575	FlyBaseID:	FBgn0051065	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_510243.1	Gene:	flr-1 / 181468	WormBaseID:	WBGene00001465	Length:	638	Species:	Caenorhabditis elegans

Alignment Length:	433	Identity:	79/433 - (18%)
Similarity:	162/433 - (37%)	Gaps:	69/433 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SMILYLVTFYHTLPFFANVSLSLLNSYLSSSVSFNLDTIYLNWNSTFPAITVCEI--YNAERIWD 64
            |.|.::|.....|..|...|..||..|.:....|..:||.......||.:|:|.:  .|..::.:
Worm    42 SRIFWVVVVLSCLSLFMIHSGYLLLGYHAKPTLFQTNTIVPMNGLLFPEVTICNLNPLNTTKLEE 106

  Fly    65 LSDSN------FG----VEHDMHVDDFISEIVFYRGVCSSCEDCSRMRCPSNFTHLVDVFRTKCH 119
            |:.|.      ||    :....|....:.|..|.. :.::.::.::..  .|..:.:......|.
Worm   107 LNISKSTWTYIFGYFDEITTSEHKSTKLGEEQFLE-IMNNYQELTKQE--FNVKNFLKSVSKSCE 168

  Fly   120 QLLVNCTY-LNKLFDCCDQFLPLPTEYGLCFSFNSHQARKVSHLQFTNNR------MTGPGHLSF 177
            :..::|:: ..||.:||:......||.|:||..::  ..|.....::.|.      :.|...:..
Worm   169 ETFISCSFGREKLHNCCEHVTTEMTEVGVCFRLSN--VNKKYRQWYSGNGFGWEFVLNGNNEIDD 231

  Fly   178 HA-AADIQ------LYVHAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHNDESVQDLSMEQR 235
            || :.|.:      :.||.....|            .:..|...:....::|...|::::|:..:
Worm   232 HADSLDFEPDRGFLIMVHESEKYP------------KINSYGVAVSPDSQLHAAISMKNISLLDK 284

  Fly   236 ----RCRYGHEH----VPERQGIYDFYSYSGCVVECTVLLQLDNCNCT--SHFMAIPGQNYLPVC 290
                .|..|...    ||        |:.:.|.::|.:....:.|.|:  ::.....|.|.....
Worm   285 ANWGSCSKGWNRNDTDVP--------YTATHCEIDCKLRKVRNLCGCSPLAYSARESGSNDTICT 341

  Fly   291 DVRGLICLTRIRDKIMTERKSCECMSSCEEPEYNIIYNSADED--------DEASDEVSEIRVAL 347
            ..:...|..::|.........|:|.|.|...|:::..:.:|.|        .:...::|.:.:..
Worm   342 PYQIQQCFRKVRGLDNRWEDECDCPSECNMLEFDVTNSYSDLDGRSRGLSSSKVESDISHVSLYF 406

  Fly   348 VELPTQRYVRRVTKTILDFLISLGGLVGLFFNTSALRIVETIV 390
            ..:..:|..::......|.|.::.|.:|||...|.:.::|..:
Worm   407 SHVAYERIEQQKQLQTADLLSNIAGSMGLFLGMSTVTLLEIFI 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	<127..387	CDD:279230	51/291 (18%)
flr-1	NP_510243.1	ASC	22..450	CDD:279230	79/433 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920