Protein Alignment ppk31 and Asic1

DIOPT Version :10

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 460
• Identity: 95/460 - (20%)
• Similarity: 158/460 - (34%)
• Gaps: 166/460 - (36%)

  Fly     8 VTFYHTLPFFANVSLSLLNSYLSSSVSFNLDTIYLNWNSTFPAITVCEIYNAERIWDLSDSN--- 69
            |.:|.:.|     .::||:...::.:             .|||:|.|.. ||.|:..||..:
Mouse   110 VAYYLSYP-----HVTLLDEVATTEL-------------VFPAVTFCNT-NAVRLSQLSYPDLLY 155

  Fly    70 ----FGVEHDMHVDDFISEIVFYRGVCSSCEDCSRMRCPSNFT----HLVDVFRTKCHQL---LV 123
                .|::..   ||        .||..:...      |..|:    :|...:...||:|   |:
Mouse   156 LAPMLGLDES---DD--------PGVPLAPPG------PEAFSGEPFNLHRFYNRSCHRLEDMLL 203

  Fly   124 NCTYLNKLFDC---C--DQFLPLPTEYGLCFSFNSHQARKVSHLQFTNNRMTGPGHLSFHAAADI 183
            .|:|      |   |  ..|..:.|.||.|::|||.|..: ..|: |....||.|   .....||
Mouse   204 YCSY------CGGPCGPHNFSVVFTRYGKCYTFNSGQDGR-PRLK-TMKGGTGNG---LEIMLDI 257

  Fly   184 QLYVHAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHNDES---VQDL------------SME 233
            |...:.|:       .|...||......|      :::|:.:.   :..|            |.:
Mouse   258 QQDEYLPV-------WGETDETSFEAGIK------VQIHSQDEPPFIDQLGFGVAPGFQTFVSCQ 309

  Fly   234 QRRCRYGHEHVPERQG----------IYDFYSYSGCVVECTVLLQLDNCNCTSHFMAIPGQNYLP 288
            ::|..|    :|...|          .:|.||.:.|.::|.....::||||  ..:.:||.  .|
Mouse   310 EQRLIY----LPSPWGTCNAVTMDSDFFDSYSITACRIDCETRYLVENCNC--RMVHMPGD--AP 366

  Fly   289 VCDVRGL-ICLTRIRDKIM-TERKSCECMSSCEEPEYNIIYNSADEDDEASDEVSEIRVALVELP 351
            .|..... .|.....|.:: .:::.|.|...|....|             ..|:|     :|::|
Mouse   367 YCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRY-------------GKELS-----MVKIP 413

  Fly   352 TQRYVRRVTK-------------TILD---------------------FLISLGGLVGLFFNTSA 382
            ::...:.:.|             .:||                     .|..:||.:|||...|.
Mouse   414 SKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASI 478

  Fly   383 LRIVE 387
            |.::|
Mouse   479 LTVLE 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	36..387	CDD:459966	89/430 (21%)
Asic1	NP_001276720.1	ENaC	63..541	CDD:273304	95/460 (21%)