Protein Alignment ppk31 and asic1

DIOPT Version :10

• Sequence 1: NP_001097944.1
• Gene: ppk31 / 318575
• FlyBaseID: FBgn0051065
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: XP_004912018.1
• Gene: asic1 / 100489966
• XenbaseID: XB-GENE-977699
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 99/493 - (20%)
• Similarity: 166/493 - (33%)
• Gaps: 181/493 - (36%)

  Fly     1 MSMILYLVT----FYHTLPFFANVSLSLLNSYLSSSVSFNLDTIYLNWNST----FPAITVC--- 54
            :|::||:.|    :|...|...                 .||.|     ||    |||:|.|
 Frog    53 LSLLLYVCTERIIYYFEYPHVT-----------------KLDEI-----STPRMIFPAVTFCNLN 95

  Fly    55 ----------EIYNAERIWDLSDSNFGVEHDMHVDDFISEIVFYRGVCSSCEDCSRMR----CPS 105
                      ::|:|..:..|.::.:.:......|:.:.||:         :|.:..|    .|.
 Frog    96 EFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEIL---------QDKANFRNFKPKPF 151

  Fly   106 NFTHLVDVFRTKCHQLLVNCTYLNKLFDC-CDQFLPLPTEYGLCFSFNSHQARKVSHLQFTNNRM 169
            |.....|.......::|::|.|..:  :| .|.|:|:.|.||.|::|||  .|.......|....
 Frog   152 NMREFYDRTGHDIREMLLSCKYRGE--ECSVDDFVPVFTRYGKCYTFNS--GRNGRSPLVTTKGG 212

  Fly   170 TGPGHLSFHAAADIQLYVHAPIDVPYQFSEGMIRETVLLGHYKELILNVIEVHNDES---VQDL- 230
            ||.|   .....|||...:.|:       .|...||......|      :::|:.:.   :..|
 Frog   213 TGNG---LELMLDIQQDEYLPV-------WGETDETSFEAGIK------VQIHSQDEPPFIDQLG 261

  Fly   231 -----------SMEQRRCRYGHEHVPERQG----------IYDFYSYSGCVVECTVLLQLDNCNC 274
                       |.:::|..|    :|...|          .:|.||.|.|.::|.....::||||
 Frog   262 FGVAPGFQTFVSCQEQRLTY----LPPPWGDCKSSAMDSEFFDTYSISACRIDCETRYLVENCNC 322

  Fly   275 TSHFMAIPGQNYLPVCDVRGLICLTRIRDK-------IMTERKS--CECMSSCEEPEYNIIYNSA 330
              ..:.:||.         ...|...:..:       .:.|:.:  |.|.:.|....|
 Frog   323 --RMVHMPGD---------AAYCTPELYKECADPALDFLVEKDNDFCVCETPCNMTRY------- 369

  Fly   331 DEDDEASDEVSEIRVALVELPTQRYVRRVTK-------------TILD----------------- 365
                  ..|:|     :|::|::...|.:.|             .:||
 Frog   370 ------GKELS-----MVKIPSKASARYLAKKYNKSEQYIAENILVLDIFFEALNYETIEQKKAY 423

  Fly   366 ----FLISLGGLVGLFFNTSALRIVETIVIC---LRYR 396
                .|..:||.:|||...|.|.::|.....   |||:
 Frog   424 EVAGLLGDIGGQMGLFIGASILTVLELFDYAYEVLRYK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk31	NP_001097944.1	ASC	36..387	CDD:459966	89/440 (20%)
asic1	XP_004912018.1	ENaC	18..507	CDD:273304	99/493 (20%)