DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12118 and mmadhcb

DIOPT Version :9

Sequence 1:	NP_572537.1	Gene:	CG12118 / 31857	FlyBaseID:	FBgn0030101	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_991157.2	Gene:	mmadhcb / 402886	ZFINID:	ZDB-GENE-040704-50	Length:	297	Species:	Danio rerio

Alignment Length:	201	Identity:	57/201 - (28%)
Similarity:	89/201 - (44%)	Gaps:	22/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 LTAERGNR---FYLPNGIGPAWQGDSTTVGLLEPLGHLVNFHKGPN-TDKSRLEFTCCKCPLLIR 148
            |||:..|:   |.|...|....:.|.|:..        .|..|... .|.|.:|.....||.|::
Zfish   101 LTAQSNNQRHDFILAQFINELHEDDKTSTA--------QNMDKAEQFFDHSSVECAIQSCPELLK 157

  Fly   149 VPLLEIFP-VPVVAQQCINIT------MLVLSHEGDIEMG--AAKFVLAAREMCDRLLSYGYWAD 204
            .....:|| .|......:.:|      |...:.:.|.|..  .|||:..|:|:|..|.:.|:|||
Zfish   158 RDFESMFPEAPSTGMMVVTVTQRTQNDMTAWTEQVDQEREELLAKFIEGAKEICHALRNEGFWAD 222

  Fly   205 FMNPFSGRPFFLPREGANLYRLDSRFRGLNMRLSEQNRCTVISAEKNDSTRFSGTIYSTAPNHYG 269
            |::|.||..:|.......|:..|.|:|.|..::.:...|.||......:..|.||::::||.: .
Zfish   223 FIDPSSGLAYFGSYTNNTLFETDDRYRHLGFQIEDLGCCKVIRHVMWGTHAFVGTLFTSAPPN-S 286

  Fly   270 QLMKLL 275
            |:||.|
Zfish   287 QIMKKL 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12118	NP_572537.1	DUF2246	22..275	CDD:287231	56/199 (28%)
mmadhcb	NP_991157.2	DUF2246	24..293	CDD:287231	57/201 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9613
eggNOG	1	0.900	-	-		E1_KOG3994
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5325
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1363001at2759
OrthoFinder	1	1.000	-	-		FOG0006544
OrthoInspector	1	1.000	-	-		otm24685
orthoMCL	1	0.900	-	-		OOG6_105788
Panther	1	1.100	-	-	O	PTHR13192
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4433
SonicParanoid	1	1.000	-	-		X5533
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.860