Protein Alignment CG12118 and MMADHC

DIOPT Version :9

• Sequence 1: NP_572537.1
• Gene: CG12118 / 31857
• FlyBaseID: FBgn0030101
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_056517.1
• Gene: MMADHC / 27249
• HGNCID: 25221
• Length: 296
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 66/226 - (29%)
• Similarity: 93/226 - (41%)
• Gaps: 48/226 - (21%)

  Fly    95 RFYLPNGI-------GPAWQGDSTTVG-----LLEPL---------GHLVNFHKGPNT------- 131
            ||.||..|       |.|.|..|....     |.|||         ...||..:|.:.
Human    71 RFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYVNEFQGNDAPVEQEIN 135

  Fly   132 ------DKSRLEFTCCKCPLLIRVPLLEIFP--------VPVVAQQCINITMLVLSHEGDIEMGA 182
                  :.:|:|.....||.|:|.....:||        :..|.|:..| .|.|.|.|.:||...
Human   136 SAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQKTKN-DMTVWSEEVEIEREV 199

  Fly   183 --AKFVLAAREMCDRLLSYGYWADFMNPFSGRPFFLPREGANLYRLDSRFRGLNMRLSEQNRCTV 245
              .||:..|:|:|..|.:.||||||::|.||..||.|.....|:..|.|:|.|...:.:...|.|
Human   200 LLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKV 264

  Fly   246 ISAEKNDSTRFSGTIYSTA-PNHYGQLMKLL 275
            |......:....|:|::.| |:.:  :||.|
Human   265 IRHSLWGTHVVVGSIFTNATPDSH--IMKKL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12118	NP_572537.1	DUF2246	22..275	CDD:287231	65/224 (29%)
MMADHC	NP_056517.1	MMADHC	24..293	CDD:402023	65/224 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9880
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1363001at2759
OrthoFinder	1	1.000	-	-		FOG0006544
OrthoInspector	1	1.000	-	-		oto89478
orthoMCL	1	0.900	-	-		OOG6_105788
Panther	1	1.100	-	-	O	PTHR13192
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4433
SonicParanoid	1	1.000	-	-		X5533
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.910