DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34133 and AT1G64610

DIOPT Version :9

Sequence 1:	NP_001036772.2	Gene:	CG34133 / 318566	FlyBaseID:	FBgn0083969	Length:	1108	Species:	Drosophila melanogaster
Sequence 2:	NP_176642.1	Gene:	AT1G64610 / 842769	AraportID:	AT1G64610	Length:	647	Species:	Arabidopsis thaliana

Alignment Length:	678	Identity:	180/678 - (26%)
Similarity:	313/678 - (46%)	Gaps:	126/678 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 GVNDKERRKSAGDEDVLKQMNIYVRTRTSSGKQLTDFEILEQVPV--KNLDTGENMPLSEMRSPP 569
            |..:.|.|.....|.|.....:::.|.|.........:.|:.:.:  |...|.::   ||....|
plant     5 GDEEDEDRFFDAPEVVSDDFGLHLWTSTPESVSTRRRKFLQSMGLSFKKTATDDD---SEDELEP 66

  Fly   570 VPEGWNPLSLHILKLTSHLE----VIQKESDEESVIGIPPSIEGQQPDEEELETEDGSR------ 624
            .....|.:| .::.::|.::    :::.||...|...:.........|:..|...|.|.
plant    67 SHTDSNVVS-EVVNVSSGVKEIDLLVRNESTTSSGFDVSSVSSSDTDDQTLLARNDASSSTSTMP 130

  Fly   625 --LKKKTARIKRFFGS------TMRKTVDK--AKSIASEVSHARHKEDVADIVDAMNPE----QN 675
              |.:.::.....||.      :.|..:.|  |||...::....|      ::::|:.|    |.
plant   131 GGLSESSSSKSGSFGDFHNSPFSQRDDLLKKGAKSWLKKLGVLTH------VLESMDCESVRTQL 189

  Fly   676 IKIKASSSNKGPY-EFTKLQHVQDLSGEDTSAVWCMKFSSCGRLLATAGQDKVLRIWVL-----K 734
            .::....::|..: |.:.:...|:.|..|.| :..||||..|:.:|:||:|.|:|:|.:     .
plant   190 HQVARVQTHKKQFKELSSMCIDQEFSAHDGS-ILAMKFSPDGKYIASAGEDCVVRVWSITEEERT 253

  Fly   735 DAYPFFQ-DMRNKYNADQKSSPTPSQESLVSQHSAEEAIAMATAAEKCTGPFMP--------KPF 790
            |.|...: |....:..:|:|...|.:   ::....|:..:....:...|...:|        ||.
plant   254 DTYEVAEVDSGVYFGMNQRSQIEPLK---INNEKTEKKSSFLRKSSDSTCVVLPPTIFSISEKPL 315

  Fly   791 CTYNGHTSDLLDVSWSKNYFILSSSMDKTVRLWHISRKECLCCFQHIDFVTAIAFHPRDDRYFLS 855
            ..:.||..::||:|||:..::||||:|:|||||.:...|||..|.|.:|||.:||:|.||.||:|
plant   316 HEFKGHIGEILDLSWSEKGYLLSSSVDETVRLWRVGCDECLRTFTHNNFVTCVAFNPVDDNYFIS 380

  Fly   856 GSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYDGRCIFYN--TDQLKYHT 918
            ||:|||:|:|::...:|..:.::   ..::||..:..:.:.||:||..|.|.||:  .:||:...
plant   381 GSIDGKVRIWDVTRCRVVDYTDI---RDIVTAVCYRPDAKGAVIGSMTGNCRFYHIFENQLQMDQ 442

  Fly   919 QIHVRSTRGKNRI-GRKISGIEPMPGE---DKILVTSNDSRVRLYDLRDLNLSCKYKGYLNVSSQ 979
            :|:|   .||.:: .::|||::.:|.:   ||::|||.||::|:....|  :.||.|     :|.
plant   443 EINV---HGKKKVASKRISGLQYLPSDSDSDKVMVTSADSQIRIICGED--VICKLK-----ASS 497

  Fly   980 IK---GSFSHDGKYIIAGSENQCIYIWKTNHDYSKLSSVRRDRSD------FWEGIKAHNATVT- 1034
            ::   .||..|||:||:.||:..|.:|    .||:|.| ::..|:      .:||..:|||:|.
plant   498 LRTTSASFISDGKHIISTSEDSYINVW----SYSQLPS-KKPYSETPKSIRSYEGFLSHNASVAI 557

  Fly  1035 -------------CA-----------IFAPHPEAIIKPEPD----EISNE---KLAHNQPDPLVE 1068
                         |.           .|:|...:...||..    .:||.   ||..:...|.:
plant   558 PWLRQGRRDGLSECITDLDMKIPKVDCFSPMKGSTTWPEEKLEDVAMSNRGKLKLLRSAWQPHL- 621

  Fly  1069 QHKKGCGYVLVSADFNGAIKVFINKTKP 1096
                 .|.|:|:|.::|.|:||.|...|
plant   622 -----WGLVIVTATWDGRIRVFHNYGLP 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34133	NP_001036772.2	WD40 repeat	663..700	CDD:293791	6/41 (15%)
		WD40	704..1101	CDD:225201	140/454 (31%)
		WD40	704..1046	CDD:295369	123/395 (31%)
		WD40 repeat	707..765	CDD:293791	18/63 (29%)
		WD40 repeat	800..834	CDD:293791	18/33 (55%)
		WD40 repeat	841..878	CDD:293791	17/36 (47%)
		WD40 repeat	885..920	CDD:293791	12/36 (33%)
		WD40 repeat	935..975	CDD:293791	16/42 (38%)
		WD40 repeat	978..1003	CDD:293791	11/27 (41%)
		WD40 repeat	1034..1069	CDD:293791	10/66 (15%)
AT1G64610	NP_176642.1	WD40	<206..550	CDD:225201	119/365 (33%)
		WD40	212..525	CDD:295369	112/333 (34%)
		WD40 repeat	222..260	CDD:293791	14/37 (38%)
		WD40 repeat	265..305	CDD:293791	5/42 (12%)
		WD40 repeat	326..360	CDD:293791	18/33 (55%)
		WD40 repeat	365..399	CDD:293791	18/33 (55%)
		WD40 repeat	408..445	CDD:293791	12/36 (33%)
		WD40 repeat	457..494	CDD:293791	15/38 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0283
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	221	1.000	Inparanoid score	I1203
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1332590at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2463
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14221
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X637
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970