DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34133 and AT1G48870

DIOPT Version :9

Sequence 1:	NP_001036772.2	Gene:	CG34133 / 318566	FlyBaseID:	FBgn0083969	Length:	1108	Species:	Drosophila melanogaster
Sequence 2:	NP_001319178.1	Gene:	AT1G48870 / 841309	AraportID:	AT1G48870	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	152/562 - (27%)
Similarity:	235/562 - (41%)	Gaps:	139/562 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   595 SDEESVIGIPPSIEGQQPDEEELE-------TEDGSRLKKKTARIKRFFGSTMRKTVDKAKSIAS 652
            ||||        :||...|:::.|       |.......||:|: |..|........||
plant   110 SDEE--------LEGVDDDDDDSEEISSNASTSPSRSSSKKSAK-KWLFNCFSAGVKDK------ 159

  Fly   653 EVSHARHKEDVADIVDAMNPEQNIKIKASSSNKGPYEFTKLQHVQDLSGEDTSAVWCMKFSSCGR 717
                        |.....:.|...|:|..::.|...|.:....||.::|. ...:|.:|||..|:
plant   160 ------------DFKYKSSEETMSKVKVKTNKKSHVELSAAYMVQKINGH-KGKIWTLKFSPDGK 211

  Fly   718 LLATAGQDKVLRIW--VLKDAY--PFFQDMRNKYNADQKSSPTPSQESLV-----SQHSAEEAIA 773
            .|||.|:|.|::||  .|.|:.  .|.          ::..|...|.:||     :.|..|
plant   212 YLATGGEDGVVKIWRITLSDSLLASFL----------RQQEPINQQAALVLFPQKAFHIEE---- 262

  Fly   774 MATAAEKCTGPFMPKPFCTYNGHTSDLLDVSWSKNYFILSSSMDKTVRLWHISRKECLCCFQHID 838
                          .||....|||.|:||::||.:..:||:|.|||||||.....:||..|.|.:
plant   263 --------------TPFQELYGHTGDVLDLAWSDSNLLLSASKDKTVRLWRTGCDQCLHVFHHNN 313

  Fly   839 FVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYD 903
            :||.:.|:|.:...|.|||:|||.|:|.:.:::|..|.:|...   |:|.::..||...|||...
plant   314 YVTCVEFNPVNKNNFASGSIDGKARIWGLSEERVVAWTDVRDS---ISAISYQPNGNGFVVGCIT 375

  Fly   904 GRCIFYN--TDQLKYHTQIHVRSTRGKNRIGRKISGIEPMPG-EDKILVTSNDSRVRLYDLRDLN 965
            |.|.||.  .:.:....||.:   ||:||    |:.:|..|| .:||||:|.||:||::|  ...
plant   376 GNCRFYQILDNDVIMDEQILI---RGRNR----ITAVEFCPGSSEKILVSSEDSKVRIFD--KTQ 431

  Fly   966 LSCKYKGYLNVSSQIKGSF-SHDGKYIIAGSENQCIYIW-----------KTNHDY--------- 1009
            :..|:|...|...|...|| |..||:|::......:|:|           |::..:
plant   432 MIHKFKAPSNFGRQSSASFVSSTGKHILSVRRGVGVYLWNNDAFPSRKGAKSSRSFEYFHSPGVS 496

  Fly  1010 ---------SKLSSVRRDRSDFWEGIK----AHNATVTCAIFAPHPEAIIKPEPDEISNEKLAHN 1061
                     :|:|.|..|..:....::    :...:.:|.:.|..||            |||..|
plant   497 AVAAWTQPETKVSKVAGDDEESRRVMRKIQSSGRLSRSCRVTATWPE------------EKLLMN 549

  Fly  1062 QPD-----PLVE-QHKKGCGYVLVSADFNGAIKVFINKTKPK 1097
            ...     |:.| ...:....|:|:...:|.|:.|.|...|:
plant   550 VGSYDSNLPVGEFDLAEAWRLVIVTVSLDGMIRTFHNYGLPR 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34133	NP_001036772.2	WD40 repeat	663..700	CDD:293791	8/36 (22%)
		WD40	704..1101	CDD:225201	127/446 (28%)
		WD40	704..1046	CDD:295369	114/387 (29%)
		WD40 repeat	707..765	CDD:293791	20/66 (30%)
		WD40 repeat	800..834	CDD:293791	16/33 (48%)
		WD40 repeat	841..878	CDD:293791	14/36 (39%)
		WD40 repeat	885..920	CDD:293791	11/36 (31%)
		WD40 repeat	935..975	CDD:293791	16/40 (40%)
		WD40 repeat	978..1003	CDD:293791	8/25 (32%)
		WD40 repeat	1034..1069	CDD:293791	10/40 (25%)
AT1G48870	NP_001319178.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0283
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1332590at2759
OrthoFinder	1	1.000	-	-		FOG0001775
OrthoInspector	1	1.000	-	-		otm2463
orthoMCL	1	0.900	-	-		OOG6_102303
Panther	1	1.100	-	-	O	PTHR14221
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X637
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.820