Protein Alignment VhaAC45RP and atp6ap1a

DIOPT Version :10

• Sequence 1: NP_001036775.1
• Gene: VhaAC45RP / 318563
• FlyBaseID: FBgn0051030
• Length: 423
• Species: Drosophila melanogaster
• Sequence 2: NP_001373449.1
• Gene: atp6ap1a / 100004566
• ZFINID: ZDB-GENE-090312-136
• Length: 466
• Species: Danio rerio
• Alignment Length: 486
• Identity: 94/486 - (19%)
• Similarity: 167/486 - (34%)
• Gaps: 157/486 - (32%)

  Fly     4 ILVATLLCLIIGSCSASISGPFIFW---------------GHSRVSSQQTQALVESSSRELPLTQ 53
            :::...:|| ..:..:....|.:.|               ||: ||..:.::.:.        |.
Zfish    13 MILHVFICL-FAAAKSDEQVPLVAWASDGFVLSPVNAPSAGHT-VSMDELESYLN--------TA 67

  Fly    54 LFTEAKAIVVFVRNTTNRLEGTRY---------PKFQNL--------------VKSGAWTYLP-- 93
            |......:::|:::..:..:.|.|         ..||||              |.|.|...:|
Zfish    68 LSATPHNLLLFLQDKLSVDDFTMYGGVFGNKQDSVFQNLEAALVPSSSLWLPSVSSSAAALVPTL 132

  Fly    94 -QRSLAAEPFGLN--------ANIEVVSL-------SGHGEEDDSEILLAYNEAVNTYGRGEVLG 142
             |..:.|.|..:|        .|..|.:|       ||..:...::.:|:.|:.|    .|:||.
Zfish   133 LQNQIDAAPLYMNPETLAQLRLNASVAALLVFRLPYSGGADMMSTKEVLSGNDEV----IGQVLS 193

  Fly   143 ILGSREEEAHFLAKREAA-PGGEEEEKAKAAEG----------SEETEASFIYVAEGNKAVLSLN 196
            |:  :.:...:.|...|. |....||.:.|.:.          .:|..|.              |
Zfish   194 IM--KAQSVPYTAVFTALWPSRVVEEASPAVQSVWSRSLLQSRRDELPAP--------------N 242

  Fly   197 GPLELRVTNDTL----------------KLEEHIKQITFDDQRAKGYGRLSITFMHSGEKC---- 241
            .|||.:....|.                |.|.|       |..::.:|: .:....||..|
Zfish   243 PPLEFKEKGSTCILMWAEKLVVSQYRSGKWERH-------DLTSQTFGK-GVEPNLSGSSCNDTH 299

  Fly   242 ---------TLRFK-FSLI------------RGSWTLRNVEVEYRELKSVLVARGDEYTLPSAPL 284
                     .|.|: |.|:            |..:|:..|::||...|:........|    ||.
Zfish   300 SRLVLNYEDVLNFRSFKLLLVMNRRHYKVSARHWFTMDLVQLEYDGKKASFNGSRHIY----APS 360

  Fly   285 GFSYRCSAESVNF---LNP---ARNETIQSLLLSDFQVQPWLNGRPEYGEVYDCIGFVSAPILAG 343
            .:||||.:.|.::   |:|   ..|.....:...:||:|.:.....::....||..|.:..|..|
Zfish   361 EYSYRCESVSSSYYAQLSPHSDKDNANDWQISFENFQIQGFNVAGKDFSYASDCASFFTPGIWMG 425

  Fly   344 LFVVTLLLGILGLGISAMLSMHTPNRFESSR 374
            |....|::.:|..|:..::.:.|.:||:..:
Zfish   426 LVTSLLMVLVLTYGLHMIMQLRTMDRFDDPK 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaAC45RP	NP_001036775.1	Lamp	<242..319	CDD:480752	24/95 (25%)
atp6ap1a	NP_001373449.1	VAS1_LD	252..401	CDD:461752	33/160 (21%)
		Ac45-VOA1_TM	416..454	CDD:466669	10/37 (27%)