DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31030 and atp6ap1a

DIOPT Version :9

Sequence 1:	NP_001036775.1	Gene:	CG31030 / 318563	FlyBaseID:	FBgn0051030	Length:	423	Species:	Drosophila melanogaster
Sequence 2:	NP_001373449.1	Gene:	atp6ap1a / 100004566	ZFINID:	ZDB-GENE-090312-136	Length:	466	Species:	Danio rerio

Alignment Length:	486	Identity:	94/486 - (19%)
Similarity:	167/486 - (34%)	Gaps:	157/486 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ILVATLLCLIIGSCSASISGPFIFW---------------GHSRVSSQQTQALVESSSRELPLTQ 53
            :::...:|| ..:..:....|.:.|               ||: ||..:.::.:.        |.
Zfish    13 MILHVFICL-FAAAKSDEQVPLVAWASDGFVLSPVNAPSAGHT-VSMDELESYLN--------TA 67

  Fly    54 LFTEAKAIVVFVRNTTNRLEGTRY---------PKFQNL--------------VKSGAWTYLP-- 93
            |......:::|:::..:..:.|.|         ..||||              |.|.|...:|
Zfish    68 LSATPHNLLLFLQDKLSVDDFTMYGGVFGNKQDSVFQNLEAALVPSSSLWLPSVSSSAAALVPTL 132

  Fly    94 -QRSLAAEPFGLN--------ANIEVVSL-------SGHGEEDDSEILLAYNEAVNTYGRGEVLG 142
             |..:.|.|..:|        .|..|.:|       ||..:...::.:|:.|:.|    .|:||.
Zfish   133 LQNQIDAAPLYMNPETLAQLRLNASVAALLVFRLPYSGGADMMSTKEVLSGNDEV----IGQVLS 193

  Fly   143 ILGSREEEAHFLAKREAA-PGGEEEEKAKAAEG----------SEETEASFIYVAEGNKAVLSLN 196
            |:  :.:...:.|...|. |....||.:.|.:.          .:|..|.              |
Zfish   194 IM--KAQSVPYTAVFTALWPSRVVEEASPAVQSVWSRSLLQSRRDELPAP--------------N 242

  Fly   197 GPLELRVTNDTL----------------KLEEHIKQITFDDQRAKGYGRLSITFMHSGEKC---- 241
            .|||.:....|.                |.|.|       |..::.:|: .:....||..|
Zfish   243 PPLEFKEKGSTCILMWAEKLVVSQYRSGKWERH-------DLTSQTFGK-GVEPNLSGSSCNDTH 299

  Fly   242 ---------TLRFK-FSLI------------RGSWTLRNVEVEYRELKSVLVARGDEYTLPSAPL 284
                     .|.|: |.|:            |..:|:..|::||...|:........|    ||.
Zfish   300 SRLVLNYEDVLNFRSFKLLLVMNRRHYKVSARHWFTMDLVQLEYDGKKASFNGSRHIY----APS 360

  Fly   285 GFSYRCSAESVNF---LNP---ARNETIQSLLLSDFQVQPWLNGRPEYGEVYDCIGFVSAPILAG 343
            .:||||.:.|.::   |:|   ..|.....:...:||:|.:.....::....||..|.:..|..|
Zfish   361 EYSYRCESVSSSYYAQLSPHSDKDNANDWQISFENFQIQGFNVAGKDFSYASDCASFFTPGIWMG 425

  Fly   344 LFVVTLLLGILGLGISAMLSMHTPNRFESSR 374
            |....|::.:|..|:..::.:.|.:||:..:
Zfish   426 LVTSLLMVLVLTYGLHMIMQLRTMDRFDDPK 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31030	NP_001036775.1	ATP-synt_S1	243..377	CDD:310428	36/151 (24%)
atp6ap1a	NP_001373449.1	ATP-synt_S1	314..464	CDD:399083	34/147 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3868
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1111170at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12471
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.970