Protein Alignment CG31019 and CPA5

DIOPT Version :10

• Sequence 1: NP_733391.1
• Gene: CG31019 / 318558
• FlyBaseID: FBgn0051019
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_525124.3
• Gene: CPA5 / 93979
• HGNCID: 15722
• Length: 436
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 85/439 - (19%)
• Similarity: 142/439 - (32%)
• Gaps: 167/439 - (38%)

  Fly    42 PGQSGKAKRGHLCFD----AAFE----TGN-----LGKAE----LVGEFEYDLFLRPDTCNPRFR 89
            ||.|...:|..|.|.    ||..    ||:     |.|.|    |:|:.|   .|:|.    :..
Human    11 PGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLE---GLKPQ----KVD 68

  Fly    90 FWFNFTVDNVKQDQRVLFHIVNISKSRNLFSSGL--TPLVKS---------SSRPKWQRLSKRQV 143
            ||......::..|.||.|..:...|: .|.|.||  :.::|.         .:..|.:||.:...
Human    69 FWRGPARPSLPVDMRVPFSELKDIKA-YLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTN 132

  Fly   144 FFYRSAMHQGHYVLSFAFIFDKEEDVYQFALAWPYSYSRLQSYLNVIDARQGSDKRFTRCVLVKS 208
            .|..|:.|             ..|::|    :|
Human   133 SFSYSSYH-------------TLEEIY----SW-------------------------------- 148

  Fly   209 LQNRNVDLLTIDH--VTAKQRSTNRLDRSFIRVIVVLCRTHSSEAPASHVCQGL----------- 260
                 :|...::|  :.:|.:..|..:..  .::|:...|..|..||..:..|:
Human   149 -----IDNFVMEHSDIVSKIQIGNSFENQ--SILVLKFSTGGSRHPAIWIDTGIHSREWITHATG 206

  Fly   261 ---IEFLVGNHPIAAVLRD--NFVFKIVPMV-NPDGVFLGNNRCNL-------------MGQDMN 306
               ...:|.::....||.|  |.:...:.:| ||||....::...|             :|.|:|
Human   207 IWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271

  Fly   307 RNWHIG------------------SEFTQPELHAVKGMLKELDNSDVSRGIETDLIGIIFVCSYN 353
            |||..|                  |..::||:.|:...:....|          ...:|.:.||:
Human   272 RNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN----------FKALISIHSYS 326

  Fly   354 -------------ISFQTYQIDFVID-LHANSSMHGC-FIYGNTYEDVY 387
                         :|.|....|...| :.|...:||. :|:|:....:|
Human   327 QMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLY 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31019	NP_733391.1	Pepdidase_M14_N	55..>115	CDD:407865	19/76 (25%)
		M14_AGBL4_like	198..478	CDD:349479	46/255 (18%)
CPA5	NP_525124.3	Propep_M14	43..117	CDD:460505	20/81 (25%)
		M14_CPA	134..434	CDD:349442	52/308 (17%)