Protein Alignment CG31019 and CPA2

DIOPT Version :10

• Sequence 1: NP_733391.1
• Gene: CG31019 / 318558
• FlyBaseID: FBgn0051019
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001860.2
• Gene: CPA2 / 1358
• HGNCID: 2297
• Length: 419
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 60/336 - (17%)
• Similarity: 85/336 - (25%)
• Gaps: 179/336 - (53%)

  Fly   266 GNHPIAAVLRDNFVFKIVPMVNPDGVFLGNNRCNL-------------MGQDMNRNWHIG----- 312
            |..|....:.|.....::|:.||||......:..:             :|.|.||||..|
Human   201 GKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPG 265

  Fly   313 --SEFTQPELHAVKGMLKELDNSDVSRGIETDLIGIIFVCSYNISFQTYQIDFVIDLHANSSMHG 375
              |.......|....      ||:|    |...|                :||:       ..||
Human   266 ASSNPCSDSYHGPSA------NSEV----EVKSI----------------VDFI-------KSHG 297

  Fly   376 ---CFIYGNTYEDVYRYERHLVFPRLFASNAQDYVADHTMFNADERKAGSMRRFSCERLSDTVNA 437
               .||      .::.|.:.|:||                           ..:.|.:|.|
Human   298 KVKAFI------TLHSYSQLLMFP---------------------------YGYKCTKLDD---- 325

  Fly   438 YTLEVSMAGHYLKDGKTISLYNEDGYYRVGRNLARTLLQYYRFINILPMPIVTEVRSKRRGRNRH 502
                                ::|                            ::||..|.
Human   326 --------------------FDE----------------------------LSEVAQKA------ 336

  Fly   503 AHHSRSRSKTRYEVKPRPKTPRCHAPIAYTNLSICYDSGGGG--GSSDEG--------------- 550
            |...||...|:|:|          .||.    |:.|.:.||.  .|.|.|
Human   337 AQSLRSLHGTKYKV----------GPIC----SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRY 387

  Fly   551 GF-SPARPLAP 560
            || .|||.:.|
Human   388 GFLLPARQILP 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31019	NP_733391.1	Pepdidase_M14_N	55..>115	CDD:407865
		M14_AGBL4_like	198..478	CDD:349479	36/234 (15%)
CPA2	NP_001860.2	Propep_M14	28..102	CDD:460505
		M14_CPA	118..417	CDD:349442	60/336 (18%)