Protein Alignment CG31019 and CPA1

DIOPT Version :10

• Sequence 1: NP_733391.1
• Gene: CG31019 / 318558
• FlyBaseID: FBgn0051019
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_001859.1
• Gene: CPA1 / 1357
• HGNCID: 2296
• Length: 419
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 66/311 - (21%)
• Similarity: 102/311 - (32%)
• Gaps: 92/311 - (29%)

  Fly   138 LSKRQVFFYRSAMHQGHYVLSFAFIFDKEEDVYQFALAWPYSY-SRLQSYLNVIDARQGSDKRFT 201
            |...|:.|:|...|.|. .:.....|...:.|..|..:...|| :.::...:::|..|  ::.|.
Human    45 LEHLQLDFWRGPAHPGS-PIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQ--EQMFA 106

  Fly   202 RCVLVKSLQNRN-------------VDLLTID--HVTAKQRSTNRLDRSFIRVIVVL-CRTHSSE 250
            .....:|....|             :|||..:  |:.:|.:..|..:.   |.|.|| ..|..|:
Human   107 FRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEG---RPIYVLKFSTGGSK 168

  Fly   251 APASHVCQGL-----------------IEFLVGNHPIAAVLRDNFVFKIVPMVNPDGVFLGNNRC 298
            .||..:..|:                 |....|.......:.|.....:..:.|||| |...:..
Human   169 RPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDG-FAFTHST 232

  Fly   299 NLM--------------GQDMNRNWHIG----SEFTQPELHAVKGMLKELDNSDVSRGIETDLIG 345
            |.|              |.|.||||..|    ...:.|......|   :..||:|    |...|
Human   233 NRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHG---KFANSEV----EVKSI- 289

  Fly   346 IIFVCSYNISFQTYQIDFVIDLHANSSMHGCFIYGNTYEDVYRYERHLVFP 396
                           :|||.| |.|..   .||      .::.|.:.|::|
Human   290 ---------------VDFVKD-HGNIK---AFI------SIHSYSQLLMYP 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31019	NP_733391.1	Pepdidase_M14_N	55..>115	CDD:407865
		M14_AGBL4_like	198..478	CDD:349479	53/250 (21%)
CPA1	NP_001859.1	Propep_M14	26..100	CDD:460505	12/55 (22%)
		M14_CPA	117..417	CDD:349442	51/236 (22%)