DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31007 and Chchd2

DIOPT Version :9

Sequence 1:	NP_733412.2	Gene:	CG31007 / 318553	FlyBaseID:	FBgn0051007	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_077128.2	Gene:	Chchd2 / 14004	MGIID:	1261428	Length:	153	Species:	Mus musculus

Alignment Length:	153	Identity:	63/153 - (41%)
Similarity:	83/153 - (54%)	Gaps:	24/153 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SRGSSKDLPAVQQPKKESLPAAAPAA---SAATSTETKGPSTADR----FKDMATTAAGVAAGSA 88
            ||.|....||.:.|:..:.|..||||   :||..:....|:.|.|    ...|||||||||.|||
Mouse     7 SRTSRVTPPASRAPQMRAAPRRAPAAQPPAAAAPSAVGSPAAAPRQPGLMAQMATTAAGVAVGSA 71

  Fly    89 VGHAVGAGLTGMFQGRGQAAPAK-----EQPQQEGSLAASASQSVPKPQLVEDGPCAFELRQFLK 148
            |||.:|..:||.|.|.|.|.|||     ::||   .......||.        |||:.|::|||:
Mouse    72 VGHTLGHAITGGFSGGGSAEPAKPDITYQEPQ---GAQLQNQQSF--------GPCSLEIKQFLE 125

  Fly   149 CTEDNSSDLSVCKEFNEAMQQCR 171
            |.: |.||:.:|:.|||.::|||
Mouse   126 CAQ-NQSDVKLCEGFNEVLRQCR 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31007	NP_733412.2	CHCH	139..173	CDD:284221	16/33 (48%)
Chchd2	NP_077128.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51		15/43 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	78..106		11/30 (37%)
		Cx9C motif 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	116..126		5/9 (56%)
		Cx9C motif 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	136..146		4/9 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4090
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54220
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13523
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2188
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.910