Protein Alignment gskt and MCK1

DIOPT Version :10

• Sequence 1: NP_733426.1
• Gene: gskt / 318552
• FlyBaseID: FBgn0046332
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_014092.1
• Gene: MCK1 / 855409
• SGDID: S000005251
• Length: 375
• Species: Saccharomyces cerevisiae
• Alignment Length: 367
• Identity: 156/367 - (42%)
• Similarity: 212/367 - (57%)
• Gaps: 27/367 - (7%)

  Fly     1 MASQSKNSGLTNKVTTVVATNAFGADVMSEISYTDAKV-------VGNGSFGVVFQAKMVPSNE- 57
            |:::.:|.....:.:..:|.     ||.|..|....::       :|.|:||.|.||.:....:
Yeast     1 MSTEEQNGVPLQRGSEFIAD-----DVTSNKSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKN 60

  Fly    58 ---MVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKV 119
               ..|||||.....:|:|||||:|...|.||:.|::||.....:.::||.:|.||.|||||...
Yeast    61 WLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIE 125

  Fly   120 ERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQL 184
            ..:|...|..:|:..:|||.||:.|.|.|||.||.|||||||.|:|:|.||||||:|||||||:|
Yeast   126 INRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKL 190

  Fly   185 ISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKV 249
            ...:|::||||||:|||||||.|.|.|||:||:|..||||.|:|:|:.||.|...:.|:.||.|:
Yeast   191 EHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKL 255

  Fly   250 MGTPTSEQLHDMNPHY--KQFKLPEL---KPHPWSKVFRIRTPAEAIDLVSKMLIYSPNARVSPL 309
            :|.|....:...||.|  ..|..|..   ....:.|.|....| :.|||:.|:|:|.|..|:||.
Yeast   256 LGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGP-DGIDLLMKILVYEPQQRLSPR 319

  Fly   310 MGCAHPFFDELRQDPHQQLPNGRS----LPPLFNFTDYEKTI 347
            ...||.||:|||.| ...||.|.:    ||.||:|.|:|..|
Yeast   320 RILAHQFFNELRND-DTFLPRGFTEPIKLPNLFDFNDFELQI 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gskt	NP_733426.1	STKc_GSK3	30..320	CDD:271039	135/305 (44%)
MCK1	NP_014092.1	STKc_GSK3	39..330	CDD:271039	134/291 (46%)