DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gskt and SK42

DIOPT Version :9

Sequence 1:	NP_733426.1	Gene:	gskt / 318552	FlyBaseID:	FBgn0046332	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001185256.1	Gene:	SK42 / 842162	AraportID:	AT1G57870	Length:	443	Species:	Arabidopsis thaliana

Alignment Length:	345	Identity:	204/345 - (59%)
Similarity:	262/345 - (75%)	Gaps:	6/345 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VVATNAFGADVMSE--ISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMR 79
            |:.|...|.:..|.  :||....|||.||||:|||||...:.|:|||||||||:|:||||||||:
plant    64 VITTTLPGRNGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKNRELQIMQ 128

  Fly    80 KLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLR 144
            .|.|.|::.||..|:|..| .:|||||||:||:|||:.:..|.|:|..|.:|:.:|:||.||:.|
plant   129 MLDHPNVVCLKHSFYSRTE-NEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICR 192

  Fly   145 SMGYLHS-LGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGS 208
            .:.|||: .|.|||||||||:|::..|..||:|||||||.|:.||||:||||||||||||||||:
plant   193 GLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGA 257

  Fly   209 TDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPEL 273
            |:|||.||:||.||||:||||||.:|||:|||||:|||:||:||||.|::..|||:|.:||.|::
plant   258 TEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQI 322

  Fly   274 KPHPWSKVFRIRTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLF 338
            |||||.|||:.|.|.||:||:.:...||||.|.:.:..|.|||||||| ||:.:|||||.|||||
plant   323 KPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELR-DPNARLPNGRPLPPLF 386

  Fly   339 NFTDYEKT-IEPDTMPLLLP 357
            ||...|.: |.|:|:..|:|
plant   387 NFKPQELSGIPPETVDRLVP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gskt	NP_733426.1	STKc_GSK3	30..320	CDD:271039	177/292 (61%)
gskt	NP_733426.1	S_TKc	33..317	CDD:214567	173/284 (61%)
SK42	NP_001185256.1	STKc_GSK3	77..369	CDD:271039	177/292 (61%)
SK42	NP_001185256.1	S_TKc	82..366	CDD:214567	173/284 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	418	1.000	Domainoid score	I124
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I363
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D990896at2759
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	1	1.000	-	-		mtm986
orthoMCL	1	0.900	-	-		OOG6_100482
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830